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Literature DB >> 6180180

Polypurine tract adjacent to the U3 region of the Rous sarcoma virus genome provides a cis-acting function.

Abstract

The v-src coding region was deleted from cloned Rous sarcoma virus DNA, and the deleted clones were tested for infectivity by transfection. All of the coding region, as well as most of the sequences lying between v-src and the unique 3' region (U3), could be deleted without affecting viability. However, at least 9 and at most 29 of the nucleotides in the purine-rich tract adjacent to U3 were necessary for growth, even in the presence of a helper virus. It is concluded that these nucleotides (the polypurine tract) provide a cis-acting function necessary for retrovirus replication.

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Year: 1982 PMID： 6180180 PMCID： PMC256151

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

22 in total

1. Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells.

Authors: H E Varmus; S Heasley; H J Kung; H Oppermann; V C Smith; J M Bishop; P R Shank
Journal: J Mol Biol Date: 1978-03-25 Impact factor: 5.469

2. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors: A J Berk; P A Sharp
Journal: Cell Date: 1977-11 Impact factor: 41.582

3. Production of a discrete, infectious, double-stranded DNA by reverse transcription in virions of Moloney murine leukemia virus.

Authors: D Baltimore; E Gilboa; E Rothenberg; F Yoshimura
Journal: Cold Spring Harb Symp Quant Biol Date: 1979

4. Synthesis of a 600-nucleotide-long plus-strand DNA by virions of Moloney murine leukemia virus.

Authors: S W Mitra; S Goff; E Gilboa; D Baltimore
Journal: Proc Natl Acad Sci U S A Date: 1979-09 Impact factor: 11.205

5. Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA.

Authors: P R Shank; S H Hughes; H J Kung; J E Majors; N Quintrell; R V Guntaka; J M Bishop; H E Varmus
Journal: Cell Date: 1978-12 Impact factor: 41.582

Review 6. Retroviruses.

Authors: J M Bishop
Journal: Annu Rev Biochem Date: 1978 Impact factor: 23.643

7. A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors: F L Graham; A J van der Eb
Journal: Virology Date: 1973-04 Impact factor: 3.616

8. An avian oncovirus mutant (SE 21Q1b) deficient in genomic RNA: biological and biochemical characterization.

Authors: M Linial; E Medeiros; W S Hayward
Journal: Cell Date: 1978-12 Impact factor: 41.582

9. DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

Authors: M Wigler; A Pellicer; S Silverstein; R Axel; G Urlaub; L Chasin
Journal: Proc Natl Acad Sci U S A Date: 1979-03 Impact factor: 11.205

10. Intracellular restriction on the growth of induced subgroup E avian type C viruses in chicken cells.

Authors: H L Robinson
Journal: J Virol Date: 1976-06 Impact factor: 5.103

32 in total

1. Development of avian sarcoma and leukosis virus-based vector-packaging cell lines.

Authors: A W Stoker; M J Bissell
Journal: J Virol Date: 1988-03 Impact factor: 5.103

2. Specificities involved in the initiation of retroviral plus-strand DNA.

Authors: G X Luo; L Sharmeen; J Taylor
Journal: J Virol Date: 1990-02 Impact factor: 5.103

3. Plus-strand origin for human immunodeficiency virus type 1: implications for integration.

Authors: K A Pullen; J J Champoux
Journal: J Virol Date: 1990-12 Impact factor: 5.103

4. The role of Moloney murine leukemia virus RNase H activity in the formation of plus-strand primers.

Authors: A J Rattray; J J Champoux
Journal: J Virol Date: 1987-09 Impact factor: 5.103

5. Evidence of sequences resembling avian retrovirus long terminal repeats flanking the trout protamine gene.

Authors: J M Jankowski; J C States; G H Dixon
Journal: J Mol Evol Date: 1986 Impact factor: 2.395

6. Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol.

Authors: R Moore; M Dixon; R Smith; G Peters; C Dickson
Journal: J Virol Date: 1987-02 Impact factor: 5.103

7. Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5' plus-strand DNA ends in vivo.

Authors: E Bacharach; J Gonsky; D Lim; S P Goff
Journal: J Virol Date: 2000-05 Impact factor: 5.103