Literature DB >> 6179878

Immunological cross-reactivity in the absence of DNA homology between Pseudomonas toxin A and diphtheria toxin.

J C Sadoff, G A Buck, B H Iglewski, M J Bjorn, N B Groman.   

Abstract

The immunodominant determinant of Pseudomonas toxin A was shown to cross-react with a normally inaccessible determinant in fragment A of diphtheria toxin. Trypsin-treated diphtheria toxin and fragment A of diphtheria toxin inhibited binding of toxin A antibody to whole toxin A, whereas whole diphtheria toxin did not inhibit this reaction. However, even at the lowest stringency no hybridization was detected between diphtheria tox probe and Pseudomonas aeruginosa DNA.

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Year:  1982        PMID： 6179878      PMCID： PMC347520          DOI： 10.1128/iai.37.1.250-254.1982

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.609


  23 in total

1.  NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,.

Authors:  B H Iglewski; D Kabat
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

Review 2.  Diphtheria toxin: mode of action and structure.

Authors:  R J Collier
Journal:  Bacteriol Rev       Date:  1975-03

3.  An immunological study of the diphtheria toxin molecule.

Authors:  A M Pappenheimer; T Uchida; A A Harper
Journal:  Immunochemistry       Date:  1972-09

4.  Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments.

Authors:  R J Collier; J Kandel
Journal:  J Biol Chem       Date:  1971-03-10       Impact factor: 5.157

5.  Synthesis of diphtheria toxin in E. coli cell-free lysate.

Authors:  H N Lightfoot; B H Iglewski
Journal:  Biochem Biophys Res Commun       Date:  1974-01-23       Impact factor: 3.575

6.  Size of the chromosome of Pseudomonas aeruginosa PAO.

Authors:  J M Pemberton
Journal:  J Bacteriol       Date:  1974-09       Impact factor: 3.490

7.  Antigenic relationships on the diphtheria toxin molecule: antitoxin versus antitoxoid.

Authors:  M B Rittenberg; C T Pinney; B H Iglewski
Journal:  Infect Immun       Date:  1976-07       Impact factor: 3.441

8.  Large-scale purification and characterization of the exotoxin of Pseudomonas aeruginosa.

Authors:  S H Leppla
Journal:  Infect Immun       Date:  1976-10       Impact factor: 3.441

9.  Analysis of parameters affecting the solid phase radioimmunoassay quantitation of antibody to meningococcal antigens.

Authors:  W D Zollinger; J M Dalrymple; M S Artenstein
Journal:  J Immunol       Date:  1976-11       Impact factor: 5.422

10.  Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid.

Authors:  J Holmgren
Journal:  Infect Immun       Date:  1973-12       Impact factor: 3.441
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  2 in total

Review 1.  Membrane receptors for bacterial toxins.

Authors:  L Eidels; R L Proia; D A Hart
Journal:  Microbiol Rev       Date:  1983-12

2.  Foodborne enterotoxigenic Escherichia coli: detection and enumeration by DNA colony hybridization.

Authors:  W E Hill; J M Madden; B A McCardell; D B Shah; J A Jagow; W L Payne; B K Boutin
Journal:  Appl Environ Microbiol       Date:  1983-04       Impact factor: 4.792
  2 in total

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