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Literature DB >> 6178649

The value of exogenous interferon in adenovirus keratoconjunctivitis. Preliminary results.

Abstract

Fourteen patients with confirmed adenovirus (kerato-) conjunctivitis were treated at random with either exogenous interferon alpha (Le) (3 x 10(6) IU/ml, 1 drop daily) or with albumin. We observed no clinically relevant therapeutic effects. However, interferon seemed to exert a prophylactic effect on uninflamed fellow eyes. The prophylactic potency of interferon in adenovirus (kerato-)conjunctivitis should be evaluated in further controlled trials.

Entities: Disease Species

Mesh：

Substances：
Interferons

Year: 1982 PMID： 6178649 DOI： 10.1007/BF02215650

Source DB: PubMed Journal: Graefes Arch Clin Exp Ophthalmol ISSN： 0721-832X Impact factor: 3.117

4 in total

1. Partial purification of human leukocyte interferon on a large scale.

Authors: K Cantell; S Hirvonen; V Koistinen
Journal: Methods Enzymol Date: 1981 Impact factor: 1.600

2. [The effects of topical steroids in epidemic kerato-conjunctivitis (author's transl)].

Authors: S Trauzettel-Klosinski; R Sundmacher; R Wigand
Journal: Klin Monbl Augenheilkd Date: 1980-06 Impact factor: 0.700

3. Comparative evaluation of human leukocyte and fibroblast interferon in the prevention of herpes simplex virus keratitis in a monkey model.

Authors: D Neumann-Haefelin; R Sundmacher; R Skoda; K Cantell
Journal: Infect Immun Date: 1977-08 Impact factor: 3.441

The value of exogenous interferon in adenovirus keratoconjunctivitis. Preliminary results.

1. Partial purification of human leukocyte interferon on a large scale.

2. [The effects of topical steroids in epidemic kerato-conjunctivitis (author's transl)].

3. Comparative evaluation of human leukocyte and fibroblast interferon in the prevention of herpes simplex virus keratitis in a monkey model.

4. [Virological diagnosis of epidemic keratoconjunctivitis (author's transl)].

1. Topical human fibroblast interferon for acute adenoviral conjunctivitis.

2. Adenoviral keratoconjunctivitis.

3. Human adenovirus: Viral pathogen with increasing importance.

Review 4. Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis.