Literature DB >> 6177036

Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin.

A F Williams, J Gagnon.   

Abstract

The amino acid sequences of mouse brain Thy-1 glycoproteins are shown to be homologous to those of variable-region immunoglobulin domains. There is also good homology with constant domains and beta 2-microglobulin; overall the results suggest that Thy-1 may be like the primordial immunoglobulin domain. Preliminary evidence for an invertebrate Thy-1 homolog supports this possibility.

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Year:  1982        PMID: 6177036     DOI: 10.1126/science.6177036

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  138 in total

1.  Ig-like domains: evolution from simple interaction molecules to sophisticated antigen recognition.

Authors:  A N Barclay
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

2.  Multi-level regulation of Thy-1 antigen expression in mouse T lymphomas.

Authors:  N J Fasel; N Déglon
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

3.  Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene.

Authors:  M I Nerenberg; T Minor; J Price; D N Ernst; T Shinohara; H Schwarz
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

4.  Structure of the mouse gene encoding CD4 and an unusual transcript in brain.

Authors:  S D Gorman; B Tourvieille; J R Parnes
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

5.  Thy1 associates with the cation channel subunit HCN4 in adult rat retina.

Authors:  Gloria J Partida; Tyler W Stradleigh; Genki Ogata; Iv Godzdanker; Andrew T Ishida
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-03-26       Impact factor: 4.799

6.  Characterization of a plasma membrane protein present in non-myelin-forming PNS and CNS glia, a subpopulation of PNS neurons, perineurial cells and smooth muscle in adult rats.

Authors:  R Mirsky; J Gavrilovic; P Bannerman; J Winter; K R Jessen
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

7.  Olfactory marker protein gene: its structure and olfactory neuron-specific expression in transgenic mice.

Authors:  E Danciger; C Mettling; M Vidal; R Morris; F Margolis
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

8.  Anti-Thy-1 antibody responses evoked by Thy-1 antigen expressed in transfected mouse mastocytoma cells and rat fibroblast.

Authors:  K Isobe; A Fortunato; V Giguere; F Grosveld; N A Mitchison
Journal:  Immunology       Date:  1985-11       Impact factor: 7.397

9.  Chromosomal localization of the human Thy-1 gene.

Authors:  J van Rijs; V Giguère; J Hurst; T van Agthoven; A Geurts van Kessel; S Goyert; F Grosveld
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

10.  Domain structures and molecular evolution of class I and class II major histocompatibility gene complex (MHC) products deduced from amino acid and nucleotide sequence homologies.

Authors:  K Ohnishi
Journal:  Orig Life       Date:  1984
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