Literature DB >> 6175193

The effect of captopril on plasma histamine and histamine release in vitro.

K M Taylor, D N Sharpe.   

Abstract

Plasma histamine and the release of histamine from blood in vitro has been determined in patients being treated for hypertension or heart failure with captopril. This drug does not alter plasma histamine levels in either group of patients or release histamine from human basophils, rat peritoneal mast cells or guinea pig lung slices upon challenge in vitro. We conclude that histamine release does not contribute to the cardiovascular or side effects of captopril.

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Year:  1981        PMID: 6175193     DOI: 10.1007/BF02004705

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  14 in total

1.  Clinical experience with blockade of the renin-angiotensin-aldosterone system by an oral converting-enzyme inhibitor (SQ 14,225, captopril) in hypertensive patients.

Authors:  D B Case; S A Atlas; J H Laragh; J E Sealey; P A Sullivan; D N McKinstry
Journal:  Prog Cardiovasc Dis       Date:  1978 Nov-Dec       Impact factor: 8.194

Review 2.  Histamine: its role in physiological and pathological processes.

Authors:  M A Beaven
Journal:  Monogr Allergy       Date:  1978

3.  Modification of the enzymatic isotopic assay of histamine and its application to measurement of histamine in tissues, serum and urine.

Authors:  M A Beaven; S Jacobsen; Z Horáková
Journal:  Clin Chim Acta       Date:  1972-03       Impact factor: 3.786

4.  An enzymatic-isotopic microassay for measuring allergic release of histamine from blood and mast cells in vitro.

Authors:  K M Taylor; S Krilis; B A Baldo
Journal:  Int Arch Allergy Appl Immunol       Date:  1980

Review 5.  Histamine release in clinical conditions.

Authors:  W Lorenz; A Doenicke
Journal:  Mt Sinai J Med       Date:  1978 May-Jun

6.  A sensitive and specific method for the determination of histomine in human whole blood and plasma.

Authors:  W Lorenz; H J Reimann; H Barth; J Kusche; R Meyer; A Doenicke; M Hutzel
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1972-06

7.  Histamine levels in plasma, blood, and urine in severe asthma, and the effect of corticosteroid treatment.

Authors:  C Bruce; R Weatherstone; A Seaton; W H Taylor
Journal:  Thorax       Date:  1976-12       Impact factor: 9.139

8.  Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents.

Authors:  M A Ondetti; B Rubin; D W Cushman
Journal:  Science       Date:  1977-04-22       Impact factor: 47.728

9.  H1 + H2-receptor antagonists for premedication in anaesthesia and surgery: a critical view based on randomized clinical trials with Haemaccel and various antiallergic drugs.

Authors:  W Lorenz; A Doenicke; B Schöning; J Mamorski; D Weber; E Hinterlang; B Schwarz; E Neugebauer
Journal:  Agents Actions       Date:  1980-04

10.  Low-dose captopril in chronic heart failure: acute haemodynamic effects and long-term treatment.

Authors:  D N Sharpe; J E Douglas; R J Coxon; B Long
Journal:  Lancet       Date:  1980-11-29       Impact factor: 79.321

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