Literature DB >> 6172573

Intrathecal and intraventricular morphine for pain in cancer patients: initial study.

M E Leavens, C S Hill, D A Cech, J B Weyland, J S Weston.   

Abstract

Intractable pain in six cancer patients was treated with lumbar intrathecal morphine (two patients) and intraventricular morphine (four patients). Daily percutaneous injections of morphine through Ommaya reservoirs were made. Initially, 1 mg of lumbar intrathecal morphine resulted in pain relief for 10 to 14 hours, and 2.5 to 4.0 mg of intraventricular morphine gave relief for 12 to 24 hours. This treatment was continued for 3 to 7 months in three of the adults. Morphine requirements gradually increased. Side effects were minimal, and there were no complications.

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Year:  1982        PMID: 6172573     DOI: 10.3171/jns.1982.56.2.0241

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  15 in total

Review 1.  Intrathecal drug administration. Present use and future trends.

Authors:  J S Kroin
Journal:  Clin Pharmacokinet       Date:  1992-05       Impact factor: 6.447

2.  Analgesic effect of epidural morphine in lumbar disc surgery.

Authors:  A Sepehrnia; W J van Ouwerkerk
Journal:  Neurosurg Rev       Date:  1996       Impact factor: 3.042

Review 3.  Implantable pumps for drug delivery to the brain.

Authors:  S Bakhshi; R B North
Journal:  J Neurooncol       Date:  1995-11       Impact factor: 4.130

Review 4.  History and present state of targeted intrathecal drug delivery.

Authors:  Syed Rizvi; Krishna Kumar
Journal:  Curr Pain Headache Rep       Date:  2015

5.  Utility of surgery in the treatment of epidural vertebral metastases.

Authors:  A García-Picazo; P Capilla Ramírez; P Pulido Rivas; R Garcia de Sola
Journal:  Acta Neurochir (Wien)       Date:  1990       Impact factor: 2.216

Review 6.  Intracerebroventricular opioids for intractable pain.

Authors:  Robert B Raffa; Joseph V Pergolizzi
Journal:  Br J Clin Pharmacol       Date:  2012-07       Impact factor: 4.335

Review 7.  Opioid analgesics: comparative features and prescribing guidelines.

Authors:  N I Cherny
Journal:  Drugs       Date:  1996-05       Impact factor: 9.546

Review 8.  Intrathecal pumps.

Authors:  Shawn Belverud; Alon Mogilner; Michael Schulder
Journal:  Neurotherapeutics       Date:  2008-01       Impact factor: 7.620

9.  Management of intractable pain in cancer patients by implantable morphine infusion systems.

Authors:  G C Dennis; R DeWitty
Journal:  J Natl Med Assoc       Date:  1987-09       Impact factor: 1.798

10.  The cause of failure in high cervical percutaneous cordotomy: an analysis.

Authors:  J J Mooij; D A Bosch; J W Beks
Journal:  Acta Neurochir (Wien)       Date:  1984       Impact factor: 2.216

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