Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Enhancement of ribosomal ribonucleic acid synthesis by deoxyribonucleic acid gyrase activity in Escherichia coli.

Literature DB >> 6171557

Enhancement of ribosomal ribonucleic acid synthesis by deoxyribonucleic acid gyrase activity in Escherichia coli.

B A Oostra, A J van Vliet, G Ab, M Gruber.

Abstract

The effect of the deoxyribonucleic acid (DNA) gyrase inhibitors coumermycin A1, novobiocin, and oxolinic acid on ribonucleic acid (RNA) synthesis in Escherichia coli was studied in vivo and in vitro. Preferential inhibition of ribosomal RNA (rRNA) synthesis was observed. No effect of oxolinic acid and coumermycin on rRNA synthesis was seen in mutants having a DNA gyrase which is resistant to these inhibitors. In a temperature-sensitive DNA gyrase mutant rRNA synthesis was decreased at nonpermissive temperatures. Thus, a functional DNA gyrase is required for rRNA synthesis. Purified DNA gyrase had no effect on rRNA synthesis in a purified system. However, DNA gyrase does show preferential stimulation of rRNA synthesis in a system supplemented with other proteins. Apparently, DNA gyrase stimulation of rRNA synthesis requires another protein.

Entities: Chemical Species

Mesh：

Substances：

Year: 1981 PMID： 6171557 PMCID： PMC216275 DOI： 10.1128/jb.148.3.782-787.1981

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

32 in total

1. Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase.

Authors: H L Yang; K Heller; M Gellert; G Zubay
Journal: Proc Natl Acad Sci U S A Date: 1979-07 Impact factor: 11.205

2. Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase.

Authors: C L Smith; M Kubo; F Imamoto
Journal: Nature Date: 1978-10-05 Impact factor: 49.962

3. Angular alteration of the DNA helix by E. coli RNA polymerase.

Authors: J M Saucier; J C Wang
Journal: Nat New Biol Date: 1972-10-11

4. Specific stimulation of ribosomal RNA synthesis in E. coli by a protein factor.

Authors: B A Oostra; G Ab; M Gruber
Journal: Mol Gen Genet Date: 1980-01

5. DNA supercoiling and transcription in Escherichia coli: influence of RNA polymerase mutations.

Authors: S M Mirkin; E S Bogdanova; Z M Gorlenko; A I Gragerov; O A Larionov
Journal: Mol Gen Genet Date: 1979

Review 6. DNA gyrase and the supercoiling of DNA.

Authors: N R Cozzarelli
Journal: Science Date: 1980-02-29 Impact factor: 47.728

7. Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase.

Authors: B Sanzey
Journal: J Bacteriol Date: 1979-04 Impact factor: 3.490

8. Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth.

Authors: K N Kreuzer; N R Cozzarelli
Journal: J Bacteriol Date: 1979-11 Impact factor: 3.490

9. In vivo enhancement of general and specific transcription in Escherichia coli by DNA gyrase activity.

Authors: M Kubo; Y Kano; H Nakamura; A Nagata; F Imamoto
Journal: Gene Date: 1979-10 Impact factor: 3.688

10. Chromosomes in living Escherichia coli cells are segregated into domains of supercoiling.

Authors: R R Sinden; D E Pettijohn
Journal: Proc Natl Acad Sci U S A Date: 1981-01 Impact factor: 11.205

9 in total

1. Long-term experimental evolution in Escherichia coli. XII. DNA topology as a key target of selection.

Authors: Estelle Crozat; Nadège Philippe; Richard E Lenski; Johannes Geiselmann; Dominique Schneider
Journal: Genetics Date: 2004-10-16 Impact factor: 4.562

2. Coupling between DNA replication and cell division mediated by the FtsA protein in Escherichia coli: a pathway independent of the SOS response, the "TER" pathway.

Authors: A Tormo; A Dopazo; A G de la Campa; M Aldea; M Vicente
Journal: J Bacteriol Date: 1985-11 Impact factor: 3.490

Enhancement of ribosomal ribonucleic acid synthesis by deoxyribonucleic acid gyrase activity in Escherichia coli.

1. Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase.

2. Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase.

3. Angular alteration of the DNA helix by E. coli RNA polymerase.

4. Specific stimulation of ribosomal RNA synthesis in E. coli by a protein factor.

5. DNA supercoiling and transcription in Escherichia coli: influence of RNA polymerase mutations.

Review 6. DNA gyrase and the supercoiling of DNA.

7. Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase.

8. Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth.

9. In vivo enhancement of general and specific transcription in Escherichia coli by DNA gyrase activity.

10. Chromosomes in living Escherichia coli cells are segregated into domains of supercoiling.

1. Long-term experimental evolution in Escherichia coli. XII. DNA topology as a key target of selection.

2. Coupling between DNA replication and cell division mediated by the FtsA protein in Escherichia coli: a pathway independent of the SOS response, the "TER" pathway.

Review 3. DNA supercoiling and environmental regulation of gene expression in pathogenic bacteria.

Review 4. The regulation of ribosomal RNA synthesis and bacterial cell growth.

5. Changes in the linking number of supercoiled DNA accompany growth transitions in Escherichia coli.

6. Energy buffering of DNA structure fails when Escherichia coli runs out of substrate.

Review 7. Biology of bacterial deoxyribonucleic acid topoisomerases.

8. Spatial organization of RNA polymerase and its relationship with transcription in Escherichia coli.

Review 9. Coherent Domains of Transcription Coordinate Gene Expression During Bacterial Growth and Adaptation.