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Literature DB >> 6164763

Short-term intensive cyclophosphamide treatment in multiple sclerosis. A retrospective controlled study.

P Theys, F Gosseye-Lissoir, P Ketelaer, H Carton.

Abstract

The effect of short-term intensive cyclophosphamide therapy upon 21 patients with moderately advanced multiple sclerosis is compared with a non-treated control group of 21 patients retrospectively matched for global disability. The progression of the disease was evaluated by regular disability scoring, and the results were analyzed by non-parametric statistical tests. No significant differences in the progression of the disability could be detected during a follow-up period of 2 years.

Entities: Chemical Disease Species

Mesh：

Substances：
Cyclophosphamide

Year: 1981 PMID： 6164763 DOI： 10.1007/BF00313325

Source DB: PubMed Journal: J Neurol ISSN： 0340-5354 Impact factor: 4.849

9 in total

1. Treatment of the chronic progressive form of multiple sclerosis with a combination of cyclophosphamide and prednisone.

Authors: O R Hommes; J J Prick; K J Lamers
Journal: Clin Neurol Neurosurg Date: 1975 Impact factor: 1.876

2. FURTHER NOTES ON DISABILITY EVALUATION IN MULTIPLE SCLEROSIS, WITH SCALE MODIFICATIONS.

Authors: J F KURTZKE
Journal: Neurology Date: 1965-07 Impact factor: 9.910

Review 3. A review of systemic nonspecific immunosuppressive treatment of multiple sclerosis.

Authors: G W Ellison; L W Myers
Journal: Neurology Date: 1978-09 Impact factor: 9.910

4. Prolonged azathioprine treatment of non-remitting multiple sclerosis.

Authors: J A Rosen
Journal: J Neurol Neurosurg Psychiatry Date: 1979-04 Impact factor: 10.154

5. Combined therapeutic trial in multiple sclerosis: hydrocortisone hemisuccinate with cyclophosphamide or cytosine arabinoside.

Authors: W Cendrowski
Journal: Acta Neurol Belg Date: 1973 Jul-Aug Impact factor: 2.396

3 in total

Short-term intensive cyclophosphamide treatment in multiple sclerosis. A retrospective controlled study.

1. Treatment of the chronic progressive form of multiple sclerosis with a combination of cyclophosphamide and prednisone.

2. FURTHER NOTES ON DISABILITY EVALUATION IN MULTIPLE SCLEROSIS, WITH SCALE MODIFICATIONS.

Review 3. A review of systemic nonspecific immunosuppressive treatment of multiple sclerosis.

4. Prolonged azathioprine treatment of non-remitting multiple sclerosis.

5. Combined therapeutic trial in multiple sclerosis: hydrocortisone hemisuccinate with cyclophosphamide or cytosine arabinoside.

6. [Evaluation and results of the rehabilitation in multiple sclerosis (author's transl)].

7. Azathioprine in multiple sclerosis--a 3 year controlled study of its effectiveness.

8. Therapeutic trial of Imuran (azathioprine) in multiple sclerosis.

9. Intensive immunosuppression with cyclophosphamide in multiple sclerosis. Follow up of 110 patients for 2-6 years.

1. Short-term intensive cyclophosphamide treatment in progressive multiple sclerosis.

2. Cyclophosphamide in relapsing remitting multiple sclerosis.

3. Immunological treatment of multiple sclerosis.