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Literature DB >> 458481

Prolonged azathioprine treatment of non-remitting multiple sclerosis.

Abstract

Two groups of 85 and 42 ambulatory patients with moderately advanced non-remitting multiple sclerosis were treated for six to 14 and three to six years with daily azathioprine. Less than 10% of these patients became confined to a wheelchair. This far exceeds any possible result in a group of non-remitting multiple sclerosis patients not so treated.

Entities: Chemical Disease Species

Mesh：

Substances：
Azathioprine

Year: 1979 PMID： 458481 PMCID： PMC490204 DOI： 10.1136/jnnp.42.4.338

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

26 in total

1. CLINICAL STUDIES OF MULTIPLE SCLEROSIS IN ISRAEL. 3. CLINICAL COURSE AND PROGNOSIS RELATED TO AGE AT ONSET.

Authors: U LEIBOWITZ; M ALTER; L HALPERN
Journal: Neurology Date: 1964-10 Impact factor: 9.910

2. PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS.

Authors: G A SCHUMACHER; G BEEBE; R F KIBLER; L T KURLAND; J F KURTZKE; F MCDOWELL; B NAGLER; W A SIBLEY; W W TOURTELLOTTE; T L WILLMON
Journal: Ann N Y Acad Sci Date: 1965-03-31 Impact factor: 5.691

3. PROGNOSTIC CRITERIA IN MULTIPLE SCLEROSIS.

Authors: H J BAUER; W FIRNHABER; W WINKLER
Journal: Ann N Y Acad Sci Date: 1965-03-31 Impact factor: 5.691

4. Lethality, duration, and mortality of disseminated sclerosis in Denmark.

Authors: K Hyllested
Journal: Acta Psychiatr Scand Date: 1961 Impact factor: 6.392

5. The benign form of multiple sclerosis. A study based on 241 cases seen within three years of onset and followed up until the tenth year or more of the disease.

Authors: D MCALPINE
Journal: Brain Date: 1961-06 Impact factor: 13.501

Review 7. Azathioprine for multiple sclerosis.

Authors: I Casetta; G Iuliano; G Filippini
Journal: Cochrane Database Syst Rev Date: 2007-10-17

8. Effectiveness of azathioprine treatment in multiple sclerosis.

Authors: L Fratiglioni; G F Siracusa; M P Amato; D Sità; L Amaducci
Journal: Ital J Neurol Sci Date: 1988-06

Review 9. Azathioprine. Safety profile in multiple sclerosis patients.

Authors: L La Mantia; N Mascoli; C Milanese
Journal: Neurol Sci Date: 2007-12 Impact factor: 3.830

9 in total

Prolonged azathioprine treatment of non-remitting multiple sclerosis.

1. CLINICAL STUDIES OF MULTIPLE SCLEROSIS IN ISRAEL. 3. CLINICAL COURSE AND PROGNOSIS RELATED TO AGE AT ONSET.

2. PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS.

3. PROGNOSTIC CRITERIA IN MULTIPLE SCLEROSIS.

4. Lethality, duration, and mortality of disseminated sclerosis in Denmark.

5. The benign form of multiple sclerosis. A study based on 241 cases seen within three years of onset and followed up until the tenth year or more of the disease.

6. Course and prognosis of disseminated sclerosis in relation to age of onset.

7. Some aspects of the natural history of disseminated sclerosis.

8. Survival in disseminated sclerosis: a clinical study of a series of cases first seen 20 years ago.

9. Multiple sclerosis: prognosis for ambulatory and nonambulatory patients.

10. Experimental allergic encephalomyelitis: the effect of 6-mercaptopurine.

1. Short-term intensive cyclophosphamide treatment in multiple sclerosis. A retrospective controlled study.

2. A double blind study on azathioprine efficacy in multiple sclerosis: final report.

Review 3. Multiple sclerosis. Current concepts in management.

4. Immunological treatment of multiple sclerosis.

5. Double blind controlled randomized study on azathioprine efficacy in multiple sclerosis. Preliminary results.

6. Azathioprine in multiple sclerosis--a 3 year controlled study of its effectiveness.

Review 7. Azathioprine for multiple sclerosis.

8. Effectiveness of azathioprine treatment in multiple sclerosis.

Review 9. Azathioprine. Safety profile in multiple sclerosis patients.