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Literature DB >> 6163870

Monoclonal antibodies against simian virus 40 tumor antigens: analysis of antigenic binding sites, using adenovirus type 2-simian virus 40 hybrid viruses.

Abstract

The antigenic binding sites of two monoclonal antibodies are located in the COOH-terminal region (clone 412) and probably in an internal region (clone 7) of simian virus 40 large T antigen. A third monoclonal antibody (clone 122), which has been shown to bind nonviral T antigen, does not react with HeLa cells infected with nondefective adenovirus type 2 (Ad2)-simian virus 40 hybrid viruses Ad2+ND1, Ad2+ND2, or Ad2+ND4.

Entities: Disease Species

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Year: 1981 PMID： 6163870 PMCID： PMC171024 DOI： 10.1128/JVI.37.1.478-482.1981

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

20 in total

1. Transplantation immunity to simian virus 40-transformed cells in tumor-bearing mice. I. Development of cellular immunity to simian virus 40 tumor-specific transplantation antigens during tumorigenesis by transplanted cells.

Authors: J M Zarling; S S Tevethia
Journal: J Natl Cancer Inst Date: 1973-01 Impact factor: 13.506

2. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors: W M Bonner; R A Laskey
Journal: Eur J Biochem Date: 1974-07-01

3. Enhancement of adenovirus plaque formation on HeLa cells by magnesium chloride.

Authors: J F Williams
Journal: J Gen Virol Date: 1970-12 Impact factor: 3.891

4. Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen.

Authors: C Prives; E Gilboa; M Revel; E Winocour
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

5. Evidence for simian virus 40 (SV40) coding of SV40 T-antigen and the SV40-specific proteins in HeLa cells infected with nondefective adenovirus type 2-SV40 hybrid viruses.

Authors: K Mann; T Hunter; G Walter; H Linke
Journal: J Virol Date: 1977-10 Impact factor: 5.103

6. Susceptibility of human diploid fibroblast strains to transformation by SV40 virus.

Authors: G J Todaro; H Green; M R Swift
Journal: Science Date: 1966-09-09 Impact factor: 47.728

7. Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VI. Characterization of the DNA from five nondefective hybrid viruses.

Authors: P H Henry; L E Schnipper; R J Samaha; C S Crumpacker; A M Lewis; A S Levine
Journal: J Virol Date: 1973-05 Impact factor: 5.103

8. Mapping of simian virus 40 early functions on the viral chromosome.

Authors: J F Morrow; P Berg; T J Kelly; A M Lewis
Journal: J Virol Date: 1973-09 Impact factor: 5.103

9. Studies on nondefective adenovirus-simian virus 40 hybrid viruses. I. A newly characterized simian virus 40 antigen induced by the Ad2+ND 1 virus.

Authors: A M Lewis; W P Rowe
Journal: J Virol Date: 1971-02 Impact factor: 5.103

10. Identification of simian virus 40 tumor and U antigens.

Authors: J A Robb
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

24 in total

1. Free and viral chromosome-bound simian virus 40 T antigen: changes in reactivity of specific antigenic determinants during lytic infection.

Authors: L C Tack; J H Wright; E G Gurney
Journal: J Virol Date: 1986-05 Impact factor: 5.103

2. Characterization of simian virus 40 large T antigen by using different monoclonal antibodies: T-p53 complexes are preferentially ATPase active and adenylylated.

Authors: L C Tack; J H Wright; E G Gurney
Journal: J Virol Date: 1988-03 Impact factor: 5.103

3. Characterization of am404, an amber mutation in the simian virus 40 T antigen gene.

Authors: D R Rawlins; P Collis; N Muzyczka
Journal: J Virol Date: 1983-07 Impact factor: 5.103

4. Protein kinase activities in immune complexes of simian virus 40 large T-antigen and transformation-associated cellular p53 protein.

Authors: F Van Roy; L Fransen; W Fiers
Journal: Mol Cell Biol Date: 1984-02 Impact factor: 4.272

5. A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system.

Authors: H Stahl; P Dröge; H Zentgraf; R Knippers
Journal: J Virol Date: 1985-05 Impact factor: 5.103

6. Plasma membrane orientation of simian virus 40 T antigen in three transformed cell lines mapped with monoclonal antibodies.

Authors: L Whittaker; A Fuks; R Hand
Journal: J Virol Date: 1985-02 Impact factor: 5.103