Literature DB >> 6163363

Electrophoretically pure mouse interferon inhibits growth, induces liver and kidney lesions, and kills suckling mice.

I Gresser, M Aguet, L Morel-Maroger, D Woodrow, F Puvion-Dutilleul, J C Guillon, C Maury.   

Abstract

Suckling Swiss mice were injected daily for 8 days with either electrophoretically pure (EP) mouse interferon (s.a. 4.7 x 10(8) units/mg protein), major impurities obtained in the course of purification, or partially purified mouse interferon (s.a. 1.3 x 10(7) units/mg protein). Only EP or partially purified interferon inhibited growth, induced liver and kidney lesions, and killed mice. The authors conclude that interferon itself is responsible for these effects.

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Year:  1981        PMID: 6163363      PMCID: PMC1903729     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN: 0002-9440            Impact factor:   4.307


  13 in total

1.  Lethality of interferon preparations for newborn mice.

Authors:  I Gresser; M G Tovey; C Maury; I Chouroulinkov
Journal:  Nature       Date:  1975-11-06       Impact factor: 49.962

2.  Progressive glomerulonephritis in mice treated with interferon preparations at birth.

Authors:  I Gresser; C Maury; M Tovey; L Morel-Maroger; F Pontillon
Journal:  Nature       Date:  1976-09-30       Impact factor: 49.962

3.  [Cytochemical analysis of polysaccharides by phosphotungstic acid treatment of ultrathin frozen sections].

Authors:  F Babaï; W Bernhard
Journal:  J Ultrastruct Res       Date:  1971-12

4.  A comparison of the efficacy of endogenous, exogenous, and combined endogenous-exogenous interferon in the treatment of mice infected with encephalomyocarditis virus.

Authors:  I Gresser; D Fontaine-Brouty-Boyé; C Bourali; M T Thomas
Journal:  Proc Soc Exp Biol Med       Date:  1969-01

5.  A method for the large scale production of potent interferon preparations.

Authors:  M G Tovey; J Begon-Lours; I Gresser
Journal:  Proc Soc Exp Biol Med       Date:  1974-07

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  Purification of mouse interferon by sequential affinity chromatography on poly(U)--and antibody--agarose columns.

Authors:  J De Maeyer-Guignard; M G Tovey; I Gresser; E De Maeyer
Journal:  Nature       Date:  1978-02-16       Impact factor: 49.962

8.  Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocytic choriomeningitis virus.

Authors:  J Gresser; L Morel-Maroger; P Verroust; Y Rivière; J C Guillon
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

9.  Inhibition by anti-interferon serum of lymphocytic choriomeningitis virus disease in suckling mice.

Authors:  Y Rivière; I Gresser; J C Guillon; M G Tovey
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

10.  Improved techniques for the preparation of ultrathin frozen sections.

Authors:  W Bernhard; A Viron
Journal:  J Cell Biol       Date:  1971-06       Impact factor: 10.539

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  20 in total

1.  Interferon induction with polyinosinic:polycytidylic acid in the newborn piglet.

Authors:  K G Loewen; J B Derbyshire
Journal:  Can J Vet Res       Date:  1986-04       Impact factor: 1.310

2.  A Brief Historical Perspective on the Pathological Consequences of Excessive Type I Interferon Exposure In vivo.

Authors:  Yanick J Crow; Pierre Lebon; Jean-Laurent Casanova; Ion Gresser
Journal:  J Clin Immunol       Date:  2018-09-05       Impact factor: 8.317

Review 3.  The interferon system as a basis for antiviral therapy or prophylaxis.

Authors:  A Billiau
Journal:  Antiviral Res       Date:  1985       Impact factor: 5.970

4.  The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene.

Authors:  D Metcalf; L Di Rago; S Mifsud; L Hartley; W S Alexander
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

5.  RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2.

Authors:  Akihiko Komuro; Curt M Horvath
Journal:  J Virol       Date:  2006-10-04       Impact factor: 5.103

6.  Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency.

Authors:  Ye Chen; Mark M W Chong; Rima Darwiche; Helen E Thomas; Thomas W H Kay
Journal:  Am J Pathol       Date:  2004-09       Impact factor: 4.307

7.  Renal deposition of alpha interferon in systemic lupus erythematosus.

Authors:  S Panem; N Ordóñez; J Vilcek
Journal:  Infect Immun       Date:  1983-10       Impact factor: 3.441

Review 8.  Negative regulation of cytoplasmic RNA-mediated antiviral signaling.

Authors:  Akihiko Komuro; Darja Bamming; Curt M Horvath
Journal:  Cytokine       Date:  2008-08-13       Impact factor: 3.861

Review 9.  Preclinical safety testing of species-specific proteins produced with recombinant DNA-techniques. An attempt to transfer current experience into future testing strategies.

Authors:  K Teelmann; C Hohbach; H Lehmann
Journal:  Arch Toxicol       Date:  1986-12       Impact factor: 5.153

10.  Renal ultrastructural markers in AIDS-associated nephropathy.

Authors:  P Chander; A Soni; A Suri; R Bhagwat; J Yoo; G Treser
Journal:  Am J Pathol       Date:  1987-03       Impact factor: 4.307

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