Literature DB >> 6163271

5-hydroxydopa, a new compound in the Raper-Mason scheme of melanogenesis.

C Hansson, H Rorsman, E Rosengren.   

Abstract

Oxidation of tyrosine or dopa by tyrosinase leads to the formation of 5-OH-dopa, a compound previously unknown in melanogenesis. 5-OH-dopa, first detected as an unknown compound on HPLC of the dopa-tyrosinase incubate, was purified by Al2O3-adsorption, semipreparative HPLC, and ion-exchange chromatography. 5-OH-dopa was identified by comparison with the authentic compound in several chromatographic systems, by electrochemical oxidation studies and by mass spectrometry.

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Year:  1980        PMID： 6163271

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN： 0001-5555            Impact factor:   4.437


  4 in total

1.  5-S-Cysteinyldopa in ganglion stellatum.

Authors:  C Fehling; C Hansson; J Poulsen; H Rorsman; E Rosengren
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

2.  The effect of cysteine on oxidation of tyrosine, dopa, and cysteinyldopas.

Authors:  G Agrup; C Hansson; H Rorsman; E Rosengren
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

3.  Chemical and enzymic oxidation by tyrosinase of 3,4-dihydroxymandelate.

Authors:  J Cabanes; A Sanchez-Ferrer; R Bru; F García-Carmona
Journal:  Biochem J       Date:  1988-12-01       Impact factor: 3.857

4.  3,4-Dihydroxyphenylethylamine, L-3,4-dihydroxyphenylalanine and 3,4,5-trihydroxyphenylalanine: oxidation and binding to membranes. A comparative study of a neurotransmitter, a precursor and a neurotransmitter candidate in primitive nervous systems.

Authors:  M Carlberg
Journal:  J Neural Transm Gen Sect       Date:  1990
  4 in total

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