Literature DB >> 61631

The effect of antithrombin III on the activity of the coagulation factors VII, IX and X.

B Osterud, M Miller-Andersson, U Abildgaard, H Prydz.   

Abstract

Antithrombin III, purified to homogeneity according to polyacrylamide gel disc electrophoresis and immunoelectrophoresis, inhibited the activity of purified factor IXa and Xa, whereas factor VII was not inhibited either in the active or in the native form. Antithrombin III is the single most important inhibitor of factor Xa in plasma. Factor Xa does not, however, reduce the activity of antithrombin III against thrombin.

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Year:  1976        PMID： 61631

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN： 0340-6245            Impact factor:   5.249


  8 in total

1.  Effect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease.

Authors:  K M Brinkhous; U Hedner; J B Garris; V Diness; M S Read
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

Review 2.  Familial venous thrombosis.

Authors:  J H Winter; A S Douglas
Journal:  Postgrad Med J       Date:  1983-11       Impact factor: 2.401

3.  Determination of antithrombin activity by an amidolytic and a clotting procedure.

Authors:  A Frigola; S Angeloni; A R Cerqueti
Journal:  J Clin Pathol       Date:  1979-01       Impact factor: 3.411

4.  The molecular-weight dependence of the rate-enhancing effect of heparin on the inhibition of thrombin, factor Xa, factor IXa, factor XIa, factor XIIa and kallikrein by antithrombin.

Authors:  E Holmer; K Kurachi; G Söderström
Journal:  Biochem J       Date:  1981-02-01       Impact factor: 3.857

5.  Isolation and sequence characterization of a cDNA clone of human antithrombin III.

Authors:  T Chandra; R Stackhouse; V J Kidd; S L Woo
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

6.  Expression of functionally active human antithrombin III.

Authors:  A W Stephens; A Siddiqui; C H Hirs
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

7.  Low-molecular-weight heparin and prevention of postoperative deep vein thrombosis.

Authors:  V V Kakkar; B Djazaeri; J Fok; M Fletcher; M F Scully; J Westwick
Journal:  Br Med J (Clin Res Ed)       Date:  1982-02-06

Review 8.  Coagulation and complement: Key innate defense participants in a seamless web.

Authors:  Edward L G Pryzdial; Alexander Leatherdale; Edward M Conway
Journal:  Front Immunol       Date:  2022-08-09       Impact factor: 8.786
  8 in total

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