Literature DB >> 6162669

The reactivation of human interferons by guanidine thiocyanate.

R J Jariwalla, J J Sedmak, S E Grossberg.   

Abstract

The addition of 1.5 M guanidine thiocyanate (GuSCN) reactivates inactive human leukocyte interferon. The biological activity of inactivated human fibroblast interferon can be only partially recovered with GuSCN if additional (thermal) energy is supplied.

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Year:  1980        PMID： 6162669     DOI： 10.1007/BF01960115

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  The influence of physicochemical factors on the thermal inactivation of murine interferon.

Authors:  R Jariwalla; S E Grossberg; J J Sedmak
Journal:  Arch Virol       Date:  1975       Impact factor: 2.574

2.  Effect of chaotropic salts and protein denaturants on the thermal stability of mouse fibroblast interferon.

Authors:  R J Jariwalla; S E Grossberg; J J Sedmak
Journal:  J Gen Virol       Date:  1977-04       Impact factor: 3.891

3.  Interferon: purification and initial characterization from human diploid cells.

Authors:  E Knight
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205

4.  Removal of sodium dodecyl sulfate from proteins.

Authors:  G P Tuszynski; L Warren
Journal:  Anal Biochem       Date:  1975-07       Impact factor: 3.365

5.  Distinct molecular species of human interferons: requirements for stabilzation and reactivation of human leukocyte and fibroblast interferons.

Authors:  W E Stewart II; P De Somer; V G Edy; K Paucker; K Berg; C A Ogburn
Journal:  J Gen Virol       Date:  1975-03       Impact factor: 3.891

6.  Stabilisation of interferons by defensive reversible denaturation.

Authors:  W E Stewart; E De Clercq; P De Somer
Journal:  Nature       Date:  1974-05-31       Impact factor: 49.962

7.  Enzymatic modifications of human fibroblast and leukocyte interferons.

Authors:  M J Otto; J J Sedmak; S E Grossberg
Journal:  J Virol       Date:  1980-08       Impact factor: 5.103

8.  Antigenic, physicochemical, and biologic characterization of human interferons.

Authors:  J Vilcek; E A Havell; S Yamazaki
Journal:  Ann N Y Acad Sci       Date:  1977-03-04       Impact factor: 5.691

9.  A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250.

Authors:  J J Sedmak; S E Grossberg
Journal:  Anal Biochem       Date:  1977-05-01       Impact factor: 3.365

10.  Inactivation of interferon: the effect of protonation.

Authors:  L W Marshall; P M Pitha; W A Carter
Journal:  Virology       Date:  1972-05       Impact factor: 3.616
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