Literature DB >> 6161991

Biochemical characterization of the virus causing leukoencephalitis and arthritis in goats.

J E Clements, O Narayan, L C Cork.   

Abstract

Goat leukoencephalitis-arthritis virus (GLV) has the density of a retrovirus in sucrose and contains an endogenous RNA-dependent DNA polymerase (reverse transcriptase). The virion reverse transcriptase utilizes the synthetic RNA template poly(rA). (dT)12 but not the synthetic DNA template poly(dA). (dT)12. A high mol. wt. RNA similar in size to visna virus RNA was isolated from 3H-uridine-labelled virions. The major structural protein of GLV has the same mol. wt. as that of visna virus. From these data the GLV appears to be a retrovirus.

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Year:  1980        PMID： 6161991     DOI： 10.1099/0022-1317-50-2-423

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  13 in total

1.  Neutralizing antibodies to visna lentivirus: mechanism of action and possible role in virus persistence.

Authors:  S Kennedy-Stoskopf; O Narayan
Journal:  J Virol       Date:  1986-07       Impact factor: 5.103

2.  Genetic variation among lentiviruses: homology between visna virus and caprine arthritis-encephalitis virus is confined to the 5' gag-pol region and a small portion of the env gene.

Authors:  J M Pyper; J E Clements; S M Molineaux; O Narayan
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

3.  Evaluation of an enzyme-linked immunosorbent assay for the detection of antibodies to caprine arthritis-encephalitis virus in goat serum.

Authors:  R A Heckert; W B McNab; S M Richardson; M R Briscoe
Journal:  Can J Vet Res       Date:  1992-07       Impact factor: 1.310

4.  Highly lytic and persistent lentiviruses naturally present in sheep with progressive pneumonia are genetically distinct.

Authors:  G Quérat; V Barban; N Sauze; P Filippi; R Vigne; P Russo; C Vitu
Journal:  J Virol       Date:  1984-11       Impact factor: 5.103

Review 5.  Caprine arthritis-encephalitis syndrome (CAE): a review.

Authors:  F K Al-Ani; J G Vestweber
Journal:  Vet Res Commun       Date:  1984-11       Impact factor: 2.459

6.  Evidence for linkage between the caprine leucocyte antigen (CLA) system and susceptibility to CAE virus-induced arthritis in goats.

Authors:  G Ruff; S Lazary
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

7.  Severity of arthritis is predicted by antibody response to gp135 in chronic infection with caprine arthritis-encephalitis virus.

Authors:  D Knowles; W Cheevers; T McGuire; T Stem; J Gorham
Journal:  J Virol       Date:  1990-05       Impact factor: 5.103

8.  Detection of caprine arthritis-encephalitis virus by polymerase chain reaction.

Authors:  P G Reddy; W J Sapp; W Heneine
Journal:  J Clin Microbiol       Date:  1993-11       Impact factor: 5.948

9.  Separate epitopes in the envelope of visna virus are responsible for fusion and neutralization: biological implications for anti-fusion antibodies in limiting virus replication.

Authors:  S E Crane; J E Clements; O Narayan
Journal:  J Virol       Date:  1988-08       Impact factor: 5.103

10.  Sialic acids on the surface of caprine arthritis-encephalitis virus define the biological properties of the virus.

Authors:  D L Huso; O Narayan; G W Hart
Journal:  J Virol       Date:  1988-06       Impact factor: 5.103
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