Literature DB >> 6161932

Recombinant human leukocyte interferon produced in bacteria has antiproliferative activity.

M Evinger, S Maeda, S Pestka.   

Abstract

Recombinant human leukocyte interferon synthesized by Escherichia coli possesses antiproliferative activity in addition to antiviral activity. When the ability to inhibit multiplication of lymphoblastoid Daudi cells was examined, the growth-inhibitory capacity of recombinant leukocyte interferon was equivalent to that exhibited by crude human leukocyte interferon or by the homogeneous gamma 2 species of leukocyte interferon synthesized by human cells.

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Year:  1981        PMID： 6161932

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  11 in total

Review 1.  Regulation of cell growth by interferon.

Authors:  M Shearer; J Taylor-Papadimitriou
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

2.  Effects of recombinant leukocyte interferon on serum immunoglobulin concentrations and lymphocyte subpopulations in chronic hepatitis B.

Authors:  H Tsuji; K Murai; K Akagi; M Fujishima
Journal:  J Clin Immunol       Date:  1990-01       Impact factor: 8.317

Review 3.  The hormonal concept of interferon. Brief review.

Authors:  A D Inglot
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574

4.  Interferon enhancement of the invasive capacity of Ewing sarcoma cells in vitro.

Authors:  G P Siegal; U P Thorgeirsson; R G Russo; D M Wallace; L A Liotta; S L Berger
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

5.  Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons.

Authors:  C W Czarniecki; C W Fennie; D B Powers; D A Estell
Journal:  J Virol       Date:  1984-02       Impact factor: 5.103

6.  A species of human alpha interferon that lacks the ability to boost human natural killer activity.

Authors:  J R Ortaldo; R B Herberman; C Harvey; P Osheroff; Y C Pan; B Kelder; S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

7.  Opposing effects of interferon produced in bacteria and of tumor promoters on myogenesis in human myoblast cultures.

Authors:  P B Fisher; A F Miranda; L E Babiss; S Pestka; I B Weinstein
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

8.  Receptor mediated pathways for interferon action: in vivo implications.

Authors:  K E Mogensen; M T Bandu; F Vignaux; G Uze; P Eid
Journal:  Med Oncol Tumor Pharmacother       Date:  1984

9.  Phase II trial of recombinant leukocyte A interferon in advanced malignant melanoma.

Authors:  U Elsässer-Beile; N Drees; H A Neumann; E Schöpf
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553

Review 10.  Adjuvant polyarthritis in rats: is this a satisfactory model for screening anti-arthritic drugs?

Authors:  K D Rainsford
Journal:  Agents Actions       Date:  1982-10
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