| Literature DB >> 6159882 |
M Tanaka, H Hibasami, J Nagai, T Ikeda.
Abstract
5-Azacytidine inhibited in vivo DNA methylation in Ehrlich's ascites tumor cells depending upon the dose at which 5-azacytidine did not inhibit DNA synthesis significantly. This drug did not inhibit DNA methylation in vitro. The DNA methylase activity in ascitic cells decreased with the increasing dose of 5-azacytidine. Hypomethylated DNA was obtained from the 5-azacytidine treated ascitic cells.Entities:
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Year: 1980 PMID： 6159882 DOI： 10.1038/icb.1980.39
Source DB: PubMed Journal: Aust J Exp Biol Med Sci ISSN： 0004-945X