| Literature DB >> 6156989 |
Abstract
Interferon treatment impairs the ability of cells to redistribute cell surface receptors for concanavalin A (Con A). The effect of interferon becomes evident within 3-6 h and is maximal within 36-48 h. Highly purified human fibroblast interferon (> 2 x 10(8) U/mg of protein sp act; concentration; 640 U/ml) caused approximately 85% inhibition of capping of fluorescein-conjugated Con A in interferon-sensitive HeLa-S3 cells at 36 h from the beginning of treatment.Entities:
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Year: 1980 PMID: 6156989 PMCID: PMC2185938 DOI: 10.1084/jem.152.2.469
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307