Literature DB >> 6156105

Implications of the reorganization of the cell genome for aging or immortalization of dividing cells in vitro.

A Macieira-Coelho.   

Abstract

Cellular aging or immortalization depends on random reorganization of the cell genome and is determined by chance, intrinsic properties of the cell and environmental factors. The probability of creating a new genetic progressively autonomous program is higher for some cells than for others and is increased by external events that introduce de novo information.

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Year:  1980        PMID： 6156105     DOI： 10.1159/000212428

Source DB:  PubMed          Journal:  Gerontology        ISSN： 0304-324X            Impact factor:   5.140


  5 in total

1.  Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts.

Authors:  W E Wright; O M Pereira-Smith; J W Shay
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

2.  Characterization of repetitive sequence families in mouse heart small polydisperse circular DNAs: age-related studies.

Authors:  S C Flores; P Sunnerhagen; T K Moore; J W Gaubatz
Journal:  Nucleic Acids Res       Date:  1988-05-11       Impact factor: 16.971

3.  Distribution of DNA between sister cells during serial subcultivation of human fibroblasts.

Authors:  A Macieira-Coelho; A Bengtsson; M Van der Ploeg
Journal:  Histochemistry       Date:  1982

4.  Tissue culture in aging research: present status and prospects.

Authors:  A Macieira-Coelho
Journal:  Experientia       Date:  1981-10-15

5.  Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi.

Authors:  Debdutta Bandyopadhyay; Jonathan L Curry; Qiushi Lin; Hunter W Richards; Dahu Chen; Peter J Hornsby; Nikolai A Timchenko; Estela E Medrano
Journal:  Aging Cell       Date:  2007-06-18       Impact factor: 9.304
  5 in total

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