Literature DB >> 6153385

Role of transcriptional regulation and enzyme inactivation in the synthesis of Escherichia coli carbamoylphosphate synthase.

A Piérard, W Lissens, P Halleux, R Cunin, N Glansdorff.   

Abstract

The question of posttranscriptional control during cumulative repression of Escherichia coli carbamoylphosphate synthase has been examined by following the kinetics of repression and by comparing messenger ribonucleic acid and enzyme levels after growth under various conditions. The data provide no evidence for control of synthesis at a level other than transcription. They suggest, however, that enzyme inactivation (or turnover) plays a significant role in the establishment of repressive conditions.

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Year:  1980        PMID： 6153385      PMCID： PMC293605          DOI： 10.1128/jb.141.1.382-385.1980

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  19 in total

1.  New features of the regulation of the tryptophan operon.

Authors:  K Bertrand; L Korn; F Lee; T Platt; C L Squires; C Squires; C Yanofsky
Journal:  Science       Date:  1975-07-04       Impact factor: 47.728

2.  Letter: Divergent transcription in the argECBH cluster of genes in Escherichia coli K12.

Authors:  P H Pouwels; R Cunin; N Glansdorff
Journal:  J Mol Biol       Date:  1974-03       Impact factor: 5.469

3.  Transient regulation of enzyme synthesis in Escherichia coli.

Authors:  E Boy; J Theze; J C Patte
Journal:  Mol Gen Genet       Date:  1973

4.  Reversible dissociation of the monomer of glutamine-dependent carbamyl phosphate synthetase into catalytically active heavy and light subunits.

Authors:  P P Trotta; L M Pinkus; R H Haschemeyer; A Meister
Journal:  J Biol Chem       Date:  1974-01-25       Impact factor: 5.157

5.  Mutations affecting uridine monophosphate pyrophosphorylase or the argR gene in Escherichia coli. Effects on carbamoyl phosphate and pyrimidine biosynthesis and on uracil uptake.

Authors:  A Piérard; N Glansdorff; J Yashphe
Journal:  Mol Gen Genet       Date:  1972

6.  Physiology and genetics of carbamoylphosphate synthesis in Escherichia coli K12.

Authors:  M Mergeay; D Gigot; J Beckmann; N Glansdorff; A Piérard
Journal:  Mol Gen Genet       Date:  1974

7.  Tryptophan messenger translation in Escherichia coli.

Authors:  R Lavallé; G De Hauwer
Journal:  J Mol Biol       Date:  1970-07-28       Impact factor: 5.469

8.  Regulation at the level of translation in the arginine pathway of Escherichia coli K12.

Authors:  R Lavallé
Journal:  J Mol Biol       Date:  1970-07-28       Impact factor: 5.469

9.  Regulation and mutation affecting a glutamine dependent formation of carbamyl phosphate in Escherichia coli.

Authors:  A Piérard; J M Wiame
Journal:  Biochem Biophys Res Commun       Date:  1964-02-18       Impact factor: 3.575

10.  Control of the biosynthesis of carbamoyl phosphate in Escherichia coli.

Authors:  A Piérard; N Glansdorff; M Mergeay; J M Wiame
Journal:  J Mol Biol       Date:  1965-11       Impact factor: 5.469
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  6 in total

Review 1.  Biosynthesis and metabolism of arginine in bacteria.

Authors:  R Cunin; N Glansdorff; A Piérard; V Stalon
Journal:  Microbiol Rev       Date:  1986-09

2.  DNA sequence of the carA gene and the control region of carAB: tandem promoters, respectively controlled by arginine and the pyrimidines, regulate the synthesis of carbamoyl-phosphate synthetase in Escherichia coli K-12.

Authors:  J Piette; H Nyunoya; C J Lusty; R Cunin; G Weyens; M Crabeel; D Charlier; N Glansdorff; A Piérard
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

3.  Multiple regulatory signals in the control region of the Escherichia coli carAB operon.

Authors:  J Bouvier; J C Patte; P Stragier
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

4.  In vitro synthesis of Escherichia coli carbamoylphosphate synthase: evidence for participation of the arginine repressor in cumulative repression.

Authors:  W Lissens; R Cunin; N Kelker; N Glansdorff; A Piérard
Journal:  J Bacteriol       Date:  1980-01       Impact factor: 3.490

5.  Molecular basis for modulated regulation of gene expression in the arginine regulon of Escherichia coli K-12.

Authors:  R Cunin; T Eckhardt; J Piette; A Boyen; A Piérard; N Glansdorff
Journal:  Nucleic Acids Res       Date:  1983-08-11       Impact factor: 16.971

Review 6.  Regulation of carbamoylphosphate synthesis in Escherichia coli: an amazing metabolite at the crossroad of arginine and pyrimidine biosynthesis.

Authors:  Daniel Charlier; Phu Nguyen Le Minh; Martine Roovers
Journal:  Amino Acids       Date:  2018-09-20       Impact factor: 3.520
  6 in total

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