Literature DB >> 6147602

Aetiology of pneumonia in children in Goroka Hospital, Papua New Guinea.

F Shann, M Gratten, S Germer, V Linnemann, D Hazlett, R Payne.   

Abstract

To determine the aetiology of pneumonia in 83 children admitted to Goroka Hospital, Papua New Guinea, lung aspirates and blood were cultured for bacteria. Haemophilus infuenzae, Streptococcus pneumoniae, or both, were isolated from 43 (52%) of the children, other bacteria from 8 (10%), and no bacteria from 32 (39%). Of the 32 strains of H influenzae tested, 18 (56%) were non-serotypable, 8 (25%) were serotypes other than type b, and only 6 (19%) were type b. Viruses were isolated from lung or nasopharyngeal aspirates from 18 (29%) of the 62 children for whom viral cultures were done. It seems that, although viruses may initiate infection, death from pneumonia in children in developing countries is often due to H influenzae, S pneumoniae, or both. Antibiotic therapy would prevent many of these deaths. There is an urgent need for vaccines, effective in children less than 6 months old, that protect against all strains of H influenzae, and S pneumoniae.

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Year:  1984        PMID: 6147602     DOI: 10.1016/s0140-6736(84)90764-5

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  72 in total

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2.  Impact on mortality of a community-based programme to control acute lower respiratory tract infections.

Authors:  V Fauveau; M K Stewart; J Chakraborty; S A Khan
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Review 3.  Pneumonia research to reduce childhood mortality in the developing world.

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4.  Pneumonia in childhood: etiology and response to antimicrobial therapy.

Authors:  O Ruuskanen; H Nohynek; T Ziegler; R Capeding; H Rikalainen; P Huovinen; M Leinonen
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-03       Impact factor: 3.267

Review 5.  Haemophilus influenzae type b vaccine.

Authors:  J R Gilsdorf
Journal:  Indian J Pediatr       Date:  1988 Mar-Apr       Impact factor: 1.967

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Authors:  D J Keeley; F K Nkrumah; C Kapuyanyika
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Review 7.  Use of vaccines as probes to define disease burden.

Authors:  Daniel R Feikin; J Anthony G Scott; Bradford D Gessner
Journal:  Lancet       Date:  2014-02-17       Impact factor: 79.321

8.  Hyponatraemia associated with pneumonia or bacterial meningitis.

Authors:  F Shann; S Germer
Journal:  Arch Dis Child       Date:  1985-10       Impact factor: 3.791

9.  Epidemiology of nasopharyngeal carriage of respiratory bacterial pathogens in children and adults: cross-sectional surveys in a population with high rates of pneumococcal disease.

Authors:  Grant A Mackenzie; Amanda J Leach; Jonathan R Carapetis; Janelle Fisher; Peter S Morris
Journal:  BMC Infect Dis       Date:  2010-10-23       Impact factor: 3.090

10.  A population-based study of hospital admission incidence rate and bacterial aetiology of acute lower respiratory infections in children aged less than five years in Bangladesh.

Authors:  Abdullah H Baqui; Mahbubur Rahman; K Zaman; Shams El Arifeen; Hafizur Rahman Chowdhury; Nazma Begum; Gaurav Bhattacharya; Rashid A Chotani; Mohammad Yunus; Mathuram Santosham; Robert E Black
Journal:  J Health Popul Nutr       Date:  2007-06       Impact factor: 2.000

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