| Literature DB >> 6146044 |
T M Pollock, E Miller, J Y Mortimer, G Smith.
Abstract
Symptoms after routine primary immunisation of 6004 infants with diphtheria/tetanus/pertussis (DTP) vaccine and 4024 infants with diphtheria/tetanus (DT) vaccine have been compared. After each dose, crying, screaming, and feverishness were more frequent with adsorbed DTP than adsorbed DT, but the difference was small. Attacks of high-pitched screaming, episodes of pallor or cyanosis with limpness, convulsions, and local reactions occurred with similar frequency after both vaccines. There was a considerable increase in local reactions after the 3rd dose with both vaccines. Over 1000 doses of plain DTP (with no aluminium hydroxide adjuvant) were given during the study. Post-vaccination symptoms were more common after the plain than after the 2 adsorbed preparations.Entities:
Keywords: Data Collection; Delivery Of Health Care; Demographic Factors; Developed Countries; Diseases--prevention and control; Europe; Health; Health Services; Immunization--side effects; Incidence; Measurement; Medicine; Morbidity; Mortality; Northern Europe; Population; Population Dynamics; Preventive Medicine; Primary Health Care; Research Methodology; Signs And Symptoms; United Kingdom; Vaccination--side effects
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Year: 1984 PMID： 6146044 DOI： 10.1016/s0140-6736(84)91057-2
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321