Literature DB >> 6143741

Enzyme histochemistry of malignant T cell lymphoma due to chronic magnesium deficiency in rats.

R Gossrau, J Vormann, T Günther.   

Abstract

The lymphocytes of the rat thymus can be grossly differentiated by their cell membrane-bound proteinases. Subcapsular thymocytes lack aminopeptidase A (APA) and AMP and gamma-glutamyltranspeptidase (GGT). Cortical thymocytes show a high activity of APA but no APM and no GGT. Medullar thymocytes possess a high GGT and APM activity but are free of APA. Under Mg deficiency, the APA-negative subcapsular thymocytes are reduced. In lymphoma and beginning lymphoma, APA, APM and GGT are absent. In lymphoma, the alkaline phosphatase activity is increased. Differences are found for dipeptidylpeptidase IV (DPP IV). In some lymphoma, its activity is reduced, in others the DPP IV activity is increased.

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Year:  1984        PMID: 6143741     DOI: 10.1007/bf00679994

Source DB:  PubMed          Journal:  Histochemistry        ISSN: 0301-5564


  17 in total

Review 1.  The pathogenesis of rat liver cancer caused by chemical carcinogens.

Authors:  G M Williams
Journal:  Biochim Biophys Acta       Date:  1980-05-06

2.  Quantitative histochemical and autoradiographic studies of hepatocarcinogenesis in rats fed 2-acetylaminofluorene followed by phenobarbital.

Authors:  T D Pugh; S Goldfarb
Journal:  Cancer Res       Date:  1978-12       Impact factor: 12.701

3.  Distribution of acid phosphatase, beta-glucuronidase and N-acetyl-beta-glucosaminise activities in lymphocytes of lymphatic tissues of man and rodents.

Authors:  N Tamaoki; E Essner
Journal:  J Histochem Cytochem       Date:  1969-04       Impact factor: 2.479

4.  Localization of gamma-glutamyl transpeptidase in lymphoid cells.

Authors:  G V Marathe; N S Damle; R H Haschemeyer; S S Tate
Journal:  FEBS Lett       Date:  1980-06-30       Impact factor: 4.124

5.  Cytochemical reactivity of T mu lymphocytes in human lymphatic tissue for dipeptidylaminopeptidase IV.

Authors:  A C Feller
Journal:  Histochem J       Date:  1982-11

Review 6.  The first relevant cell stage in rat liver carcinogenesis. A quantitative approach.

Authors:  P Emmelot; E Scherer
Journal:  Biochim Biophys Acta       Date:  1980-05-06

7.  Epithelial lymphocytes in the epididymis and intestine.

Authors:  R Gossrau
Journal:  Folia Morphol (Praha)       Date:  1980

8.  Proteinases in pathology. Usefulness of histochemical methods.

Authors:  Z Lojda
Journal:  J Histochem Cytochem       Date:  1981-03       Impact factor: 2.479

9.  Investigation of proteinases in the digestive tract using 4-methoxy-2-naphthylamine (MNA) substrates.

Authors:  R Gossrau
Journal:  J Histochem Cytochem       Date:  1981-03       Impact factor: 2.479

10.  Development and properties of malignant lymphoma induced by magnesium deficiency in rats.

Authors:  R Averdunk; P H Bippus; T Günther; H J Merker
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553

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  3 in total

1.  Proteases and antiproteases: new trends in cytochemical research.

Authors:  R Gossrau
Journal:  Histochem J       Date:  1985-05

Review 2.  Cytochemistry of membrane proteases.

Authors:  R Gossrau
Journal:  Histochem J       Date:  1985-07

3.  Enzymatic and morphological response of the thymus to drugs in normal and zinc-deficient pregnant rats and their fetuses.

Authors:  R Gossrau; H J Merker; T Günther; R Graf; J Vormann
Journal:  Histochemistry       Date:  1987
  3 in total

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