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Literature DB >> 6142304

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy.

T E Starzl, M A Nalesnik, K A Porter, M Ho, S Iwatsuki, B P Griffith, J T Rosenthal, T R Hakala, B W Shaw, R L Hardesty.

Abstract

Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts. Reduction or discontinuance of immunosuppression caused regression of the lesions, often without subsequent rejection of the grafts. Chemotherapy and irradiation were not valuable. The findings may influence policies about treating other kinds of post-transplantation neoplasms.

Entities: Chemical Disease

Mesh：

Substances：
Cyclosporins
Prednisone

Year: 1984 PMID： 6142304 PMCID： PMC2987704 DOI： 10.1016/s0140-6736(84)90994-2

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

21 in total

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Authors: S Iwatsuki; W P Geis; Z Molnar; J L Giacchino; T S Ing; J E Hano
Journal: J Surg Res Date: 1978-05 Impact factor: 2.192

Review 4. Iatrogenic alterations of immunologic surveillance in man and their influence on malignancy.

Authors: T E Starzl; I Penn; C W Putnam; C G Groth; C G Halgrimson
Journal: Transplant Rev Date: 1971

5. Five years' experience in renal transplantation with immunosuppressive drugs: survival, function, complications, and the role of lymphocyte depletion by thoracic duct fistula.

Authors: J E Murray; R E Wilson; N L Tilney; J P Merrill; W C Cooper; A G Birtch; C B Carpenter; E B Hager; G J Dammin; J H Harrison
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Journal: N Engl J Med Date: 1970-10-22 Impact factor: 91.245

7. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Authors: S M Hsu; L Raine; H Fanger
Journal: J Histochem Cytochem Date: 1981-04 Impact factor: 2.479

8. Ia antigen expression by human malignant lymphomas: correlation with conventional lymphoid markers.

Authors: J P Halper; D M Knowles; C Y Wang
Journal: Blood Date: 1980-03 Impact factor: 22.113

9. Malignant lymphomas in transplantation patients.

Authors: I Penn; W Hammond; L Brettschneider; T E Starzl
Journal: Transplant Proc Date: 1969-03 Impact factor: 1.066

10. Monoclonality of lymphoproliferative lesions in cardiac-transplant recipients. Clonal analysis based on immunoglobulin-gene rearrangements.

Authors: M L Cleary; R Warnke; J Sklar
Journal: N Engl J Med Date: 1984-02-23 Impact factor: 91.245

198 in total

1. History of clinical transplantation.

Authors: T E Starzl
Journal: World J Surg Date: 2000-07 Impact factor: 3.352

2. High levels of Epstein-Barr virus DNA in blood of solid-organ transplant recipients and their value in predicting posttransplant lymphoproliferative disorders.

Authors: F Baldanti; P Grossi; M Furione; L Simoncini; A Sarasini; P Comoli; R Maccario; R Fiocchi; G Gerna
Journal: J Clin Microbiol Date: 2000-02 Impact factor: 5.948

Review 3. Herpesvirus infections in organ transplant recipients.

Authors: Frank J Jenkins; David T Rowe; Charles R Rinaldo
Journal: Clin Diagn Lab Immunol Date: 2003-01

4. Recognition of the Epstein-Barr virus-encoded nuclear antigens EBNA-4 and EBNA-6 by HLA-A11-restricted cytotoxic T lymphocytes: implications for down-regulation of HLA-A11 in Burkitt lymphoma.

Authors: R Gavioli; P O De Campos-Lima; M G Kurilla; E Kieff; G Klein; M G Masucci
Journal: Proc Natl Acad Sci U S A Date: 1992-07-01 Impact factor: 11.205

5. The development of clinical renal transplantation.

Authors: T E Starzl
Journal: Am J Kidney Dis Date: 1990-12 Impact factor: 8.860

6. Factors in the Development of Liver Transplantation.

Authors: T E Starzl; S Iwatsuki; B W Shaw; R D Gordon; C Esquivel; S Todo; I Kam; S Lynch
Journal: Transplant Proc Date: 1985-10 Impact factor: 1.066

Review 7. Themes of liver transplantation.

Authors: Thomas E Starzl; John J Fung
Journal: Hepatology Date: 2010-06 Impact factor: 17.425