Literature DB >> 2556930

Molecular genetic analysis of lymphoid tumors arising after organ transplantation.

J Locker1, M Nalesnik.   

Abstract

A variety of gene analyses were performed on lymphoid tumors from transplant patients who received cyclosporine A for immunosuppression. Epstein-Barr virus DNA was detected in the tumors, and the structure of circular episomal virus DNA was used as a measure of cell clonality. This analysis was correlated with clonality determined by study of immunoglobulin gene rearrangement. Some of the tumors had DNA rearrangements near the c-myc gene. Analysis suggested the pathogenesis of the tumors and indicated four categories of lymphoproliferation, three neoplastic and one reactive.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2556930      PMCID： PMC1880507     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


  41 in total

1.  B-cell lymphoproliferation and lymphomagenesis are associated with clonotypic intracellular terminal regions of the Epstein-Barr virus.

Authors:  N A Brown; C R Liu; Y F Wang; C R Garcia
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

2.  The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining.

Authors:  F G Haluska; S Finver; Y Tsujimoto; C M Croce
Journal:  Nature       Date:  1986 Nov 13-19       Impact factor: 49.962

3.  An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

Authors:  D Wang; D Liebowitz; E Kieff
Journal:  Cell       Date:  1985-12       Impact factor: 41.582

Review 4.  Epstein-Barr virus as an etiological agent in the pathogenesis of lymphoproliferative and aproliferative diseases in immune deficient patients.

Authors:  D T Purtilo; E Tatsumi; G Manolov; Y Manolova; S Harada; H Lipscomb; G Krueger
Journal:  Int Rev Exp Pathol       Date:  1985

5.  Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma.

Authors:  E Cesarman; R Dalla-Favera; D Bentley; M Groudine
Journal:  Science       Date:  1987-11-27       Impact factor: 47.728

Review 6.  The approaching era of the tumor suppressor genes.

Authors:  G Klein
Journal:  Science       Date:  1987-12-11       Impact factor: 47.728

7.  The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation.

Authors:  N Raab-Traub; K Flynn
Journal:  Cell       Date:  1986-12-26       Impact factor: 41.582

8.  Expression of a transfected human c-myc oncogene inhibits differentiation of a mouse erythroleukaemia cell line.

Authors:  E Dmitrovsky; W M Kuehl; G F Hollis; I R Kirsch; T P Bender; S Segal
Journal:  Nature       Date:  1986 Aug 21-27       Impact factor: 49.962

9.  Complex translocation disrupts c-myc regulation in a human plasma cell myeloma.

Authors:  G F Hollis; A F Gazdar; V Bertness; I R Kirsch
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

10.  Epstein-Barr virus infections and DNA hybridization studies in posttransplantation lymphoma and lymphoproliferative lesions: the role of primary infection.

Authors:  M Ho; G Miller; R W Atchison; M K Breinig; J S Dummer; W Andiman; T E Starzl; R Eastman; B P Griffith; R L Hardesty
Journal:  J Infect Dis       Date:  1985-11       Impact factor: 5.226
View more
  33 in total

Review 1.  Molecular diagnosis of Epstein-Barr virus-related diseases.

Authors:  M L Gulley
Journal:  J Mol Diagn       Date:  2001-02       Impact factor: 5.568

2.  High levels of Epstein-Barr virus DNA in blood of solid-organ transplant recipients and their value in predicting posttransplant lymphoproliferative disorders.

Authors:  F Baldanti; P Grossi; M Furione; L Simoncini; A Sarasini; P Comoli; R Maccario; R Fiocchi; G Gerna
Journal:  J Clin Microbiol       Date:  2000-02       Impact factor: 5.948

3.  Epstein-Barr and human immunodeficiency viruses in acquired immunodeficiency syndrome-related primary central nervous system lymphoma.

Authors:  S Morgello
Journal:  Am J Pathol       Date:  1992-08       Impact factor: 4.307

4.  The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential.

Authors:  R Longnecker; C L Miller; X Q Miao; A Marchini; E Kieff
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

5.  An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases.

Authors:  A L Burkhardt; J B Bolen; E Kieff; R Longnecker
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

Review 6.  Lymphoproliferative disease in organ transplant recipients.

Authors:  M A Nalesnik
Journal:  Springer Semin Immunopathol       Date:  1991

7.  Epstein-Barr viral genome in lymph nodes from patients with Hodgkin's disease may not be specific to Reed-Sternberg cells.

Authors:  A Masih; D Weisenburger; M Duggan; J Armitage; R Bashir; D Mitchell; R Wickert; D T Purtilo
Journal:  Am J Pathol       Date:  1991-07       Impact factor: 4.307

8.  Development of lymphoma from the donor of haploidentical stem cell transplantation: A case report.

Authors:  Linna Xie; Fang Zhou
Journal:  Mol Clin Oncol       Date:  2017-09-19

Review 9.  Epstein-Barr virus, infectious mononucleosis, and posttransplant lymphoproliferative disorders.

Authors:  M A Nalesnik; T E Starzl
Journal:  Transplant Sci       Date:  1994-09

10.  The systemic distribution of Epstein-Barr virus genomes in fatal post-transplantation lymphoproliferative disorders. An in situ hybridization study.

Authors:  P S Randhawa; R Jaffe; A J Demetris; M Nalesnik; T E Starzl; Y Y Chen; L M Weiss
Journal:  Am J Pathol       Date:  1991-04       Impact factor: 4.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.