Literature DB >> 6135477

Characteristics of conditioned taste aversion produced by nicotine in rats.

R Kumar, J A Pratt, I P Stolerman.   

Abstract

1 Nicotine produced conditioned taste aversions in rats which were directly related to the dose of nicotine and to the number of conditioning trials. 2 The tobacco alkaloid (-)-nicotine was four to five times as potent as its stereoisomer, (+)-nicotine. 3 Mecamylamine but not hexamethonium blocked the development of taste aversions produced by nicotine. 4 Mecamylamine did not block the development of taste aversions produced by apomorphine. 5 Prolonged treatment with mecamylamine prior to conditioning did not produce supersensitivity to nicotine.

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Year:  1983        PMID： 6135477      PMCID： PMC2044849          DOI： 10.1111/j.1476-5381.1983.tb10518.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  20 in total

1.  Plasma nicotine levels after smoking cigarettes with high, medium, and low nicotine yields.

Authors:  M A Russell; C Wilson; U A Patel; C Feyerabend; P V Cole
Journal:  Br Med J       Date:  1975-05-24

2.  Supersensitivity following "pharmacological denervation".

Authors:  N EMMELIN
Journal:  Pharmacol Rev       Date:  1961-03       Impact factor: 25.468

3.  Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.

Authors:  D Tarsy; R J Baldessarini
Journal:  Neuropharmacology       Date:  1974-11       Impact factor: 5.250

4.  Area postrema damage and bait shyness.

Authors:  B D Berger; C D Wise; L Stein
Journal:  J Comp Physiol Psychol       Date:  1973-03

5.  C.N.S. effect of nicotine as the discriminative stimulus for the rat in a T-maze.

Authors:  M D Schechter; J A Rosecrans
Journal:  Life Sci I       Date:  1971-07-15

6.  Persistent behavior at high rates maintained by intravenous self-administration of nicotine.

Authors:  S R Goldberg; R D Spealman; D M Goldberg
Journal:  Science       Date:  1981-10-30       Impact factor: 47.728

7.  Absence of lithium-induced taste aversion after area postrema lesion.

Authors:  S Ritter; J J McGlone; K W Kelley
Journal:  Brain Res       Date:  1980-11-17       Impact factor: 3.252

8.  The attenuation of a specific cue-to-consequence association by antiemetic agents.

Authors:  J D Coil; W G Hankins; D J Jenden; J Garcia
Journal:  Psychopharmacology (Berl)       Date:  1978-01-31       Impact factor: 4.530

9.  Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine.

Authors:  M D Aceto; B R Martin; I M Uwaydah; E L May; L S Harris; C Izazola-Conde; W L Dewey; T J Bradshaw; W C Vincek
Journal:  J Med Chem       Date:  1979-02       Impact factor: 7.446

10.  Conditioned taste aversion and operant behavior in rats: effects of cocaine, apomorphine and some long-acting derivatives.

Authors:  G D D'Mello; D M Goldberg; S R Goldberg; I P Stolerman
Journal:  J Pharmacol Exp Ther       Date:  1981-10       Impact factor: 4.030
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  18 in total

Review 1.  Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent.

Authors:  Linda P Dwoskin; Anthony S Rauhut; Kelley A King-Pospisil; Michael T Bardo
Journal:  CNS Drug Rev       Date:  2006 Fall-Winter

2.  Apparent absence of nicotine-induced conditioned place preference in rats.

Authors:  P B Clarke; H C Fibiger
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

3.  Reduced palatability in drug-induced taste aversion: I. Variations in the initial value of the conditioned stimulus.

Authors:  Jian-You Lin; Joe Arthurs; Leslie Renee Amodeo; Steve Reilly
Journal:  Behav Neurosci       Date:  2012-03-19       Impact factor: 1.912

4.  Conditioned taste aversions: From poisons to pain to drugs of abuse.

Authors:  Jian-You Lin; Joe Arthurs; Steve Reilly
Journal:  Psychon Bull Rev       Date:  2017-04

Review 5.  Nicotine and smoking: a perspective from animal studies.

Authors:  P B Clarke
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

6.  Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine.

Authors:  Megan J Shram; Douglas Funk; Zhaoxia Li; Anh D Lê
Journal:  Psychopharmacology (Berl)       Date:  2006-04-04       Impact factor: 4.530

7.  Gustatory insular cortex lesions disrupt drug-induced, but not lithium chloride-induced, suppression of conditioned stimulus intake.

Authors:  Rastafa I Geddes; Li Han; Anne E Baldwin; Ralph Norgren; Patricia S Grigson
Journal:  Behav Neurosci       Date:  2008-10       Impact factor: 1.912

8.  Characterization of the locomotor stimulant action of nicotine in tolerant rats.

Authors:  P B Clarke; R Kumar
Journal:  Br J Pharmacol       Date:  1983-11       Impact factor: 8.739

Review 9.  Potential therapeutic uses of mecamylamine and its stereoisomers.

Authors:  Justin R Nickell; Vladimir P Grinevich; Kiran B Siripurapu; Andrew M Smith; Linda P Dwoskin
Journal:  Pharmacol Biochem Behav       Date:  2013-04-18       Impact factor: 3.533

10.  Conditioned taste aversions produced by nicotine in Roman High and Low Avoidance strains of rats.

Authors:  M J Durcan; H S Garcha; I P Stolerman
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530
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