| Literature DB >> 6132970 |
T Nishihata, J H Rytting, A Kamada, T Higuchi, M Routh, L Caldwell.
Abstract
Sodium salicylate and 5-methoxysalicylate both increased the rectal absorption of insulin in dogs when co-administered with insulin in various formulations. Microenema formulations containing 4% gelatin showed the highest insulin bioavailability of the formulations studied whereas microenemas (without gelatin) and suppository formulations were not as effective in enhancing the rectal absorption of insulin.Entities:
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Year: 1983 PMID： 6132970 DOI： 10.1111/j.2042-7158.1983.tb04294.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765