Literature DB >> 3808912

Influence of salicylate and anaesthesia on the rectal absorption of theophylline in rats.

E J Van Hoogdalem, A G De Boer, D D Breimer.   

Abstract

The effect of sodium salicylate and anaesthesia on the rectal absorption of theophylline was evaluated in rats. Theophylline proved to be slowly but completely absorbed on rectal infusion in conscious rats, compared with intravenous infusion. Pentobarbital anaesthesia did not influence absorption. In contrast to literature data, the results with salicylate showed that rectal absorption of theophylline was not enhanced.

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Year:  1986        PMID： 3808912     DOI： 10.1007/bf02280050

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  15 in total

1.  Enhancement of rectal absorption of insulin using salicylates in dogs.

Authors:  T Nishihata; J H Rytting; A Kamada; T Higuchi; M Routh; L Caldwell
Journal:  J Pharm Pharmacol       Date:  1983-03       Impact factor: 3.765

2.  Rectal administration of insulin.

Authors:  I Raz; H Bar-On; M Kidron; E Ziv
Journal:  Isr J Med Sci       Date:  1984-02

3.  Effect of salicylate on the rectal absorption of lidocaine, levodopa, and cefmetazole in rats.

Authors:  T Nishihata; J H Rytting; T Higuchi
Journal:  J Pharm Sci       Date:  1982-08       Impact factor: 3.534

4.  Dose-dependent elimination of theophylline in rats.

Authors:  M W Teunissen; I O Brorens; J M Geerlings; D D Breimer
Journal:  Xenobiotica       Date:  1985-02       Impact factor: 1.908

5.  Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level--time curve.

Authors:  W L Chiou
Journal:  J Pharmacokinet Biopharm       Date:  1978-12

6.  Effects of salicylate on rectal absorption of theophylline.

Authors:  T Nishihata; J H Rytting; T Higuchi
Journal:  J Pharm Sci       Date:  1981-01       Impact factor: 3.534

7.  Nifedipine kinetics and dynamics during rectal infusion to steady state with an osmotic system.

Authors:  C H Kleinbloesem; J van Harten; L G de Leede; P van Brummelen; D D Breimer
Journal:  Clin Pharmacol Ther       Date:  1984-09       Impact factor: 6.875

8.  Effects of diethyl ether anaesthesia on the pharmacokinetics of antipyrine and paracetamol in the rat.

Authors:  W Johannessen; G Gadeholt; J Aarbakke
Journal:  J Pharm Pharmacol       Date:  1981-06       Impact factor: 3.765

9.  Pharmacokinetics of theophylline in young children with asthma: comparison of rectal enema and suppositories.

Authors:  P Bolme; P O Edlund; M Eriksson; L Paalzow; B Winbladh
Journal:  Eur J Clin Pharmacol       Date:  1979-09       Impact factor: 2.953

10.  The effect of pentobarbitone anaesthesia and hypothermia on the hepatic clearance of indocyanine green and S(-)-acenocoumarol in the rat.

Authors:  M J Daemen; H H Thijssen; H T Vervoort-Peters; J F Smits; H A Struyker Boudier
Journal:  J Pharm Pharmacol       Date:  1986-02       Impact factor: 3.765
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