| Literature DB >> 6132268 |
M F Kagnoff, J B Weiss, R J Brown, T Lee, M S Schanfield.
Abstract
Immunoglobulin allotype markers and HLA-A, HLA-B, and HLA-DR locus antigens were determined in 30 White patients with gluten-sensitive enteropathy and 30 controls matched for age, ethnic background, and geographic origin. All patients lacking HLA-B8 and HLA-DR3 had the IgG (Gm) immunoglobulin heavy-chain phenotype Gm (f;n;b). Thus, in addition to major histocompatibility locus genes, it appears that genes linked to the immunoglobulin heavy-chain allotype locus on chromosome 14 may influence susceptibility in gluten-sensitive enteropathy.Entities:
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Year: 1983 PMID: 6132268 DOI: 10.1016/s0140-6736(83)92080-9
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321