Literature DB >> 6129364

Controlled, randomised trial of the effect of dietary fat on blood pressure.

P Puska, J M Iacono, A Nissinen, H J Korhonen, E Vartianinen, P Pietinen, R Dougherty, U Leino, M Mutanen, S Moisio, J Huttunen.   

Abstract

57 couples living in two communities of North Karelia, aged 30-50 years, were randomly allocated to three groups. After a 2-week baseline period group I followed a diet low in fat (23% of energy) with a high polyunsaturated/saturated (P/S) ratio (1 . 0), group II reduced daily salt intake from 192 mmol to 77 mmol, and group III (control group) continued the usual diet. After the 6-week intervention period groups I and II reverted to their usual diets. In group I systolic blood pressure declined from 138 . 4 to 129 . 5 mm Hg and diastolic blood pressure from 88 . 9 to 81 . 3 mm Hg during the intervention period; the values rose during switch-back. The fall was greater among hypertensive than among normotensive subjects. In groups II and III the mean blood pressure changed very little during the study.

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Year:  1983        PMID: 6129364     DOI: 10.1016/s0140-6736(83)91556-8

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  66 in total

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