| Literature DB >> 6127376 |
Abstract
The solubilization of azobenzene, menaphthone, cortisone acetate, and griseofulvin was measured in a series of non-ionic surfactants of structure CH3[CH2](m-1) [OCH2CH2]1.25m OH, where m varied from 8 to 18. Maximum solubilization occurs when m = 16 (the hexadecyl alkyl ether). This is explained in terms of changes in the oxyethylene mantle close to the micelle core/mantle interface, which appears to be the main locus of solubilization. Micellar properties of CH3[CH2]17[OCH2CH2]22OH are also reported and discussed.Entities:
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Year: 1982 PMID： 6127376 DOI： 10.1111/j.2042-7158.1982.tb04790.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765