| Literature DB >> 6126528 |
G R Pettit, Y Fujii, J A Hasler, J M Schmidt.
Abstract
Four new and relatively low molecular weight (approximately 3,000-5,000), cell growth (PS) inhibitory peptides designated palystatins A-D have been isolated from the Indian Ocean Palythao liscia Haddon and Duerden. The Isolation utilized chromatographic procedures (Amberlite XAD-7 to Sephadex G-100) guided by bioassay with the P388 murine lymphocytic leukemia (PS system). Palystatins A-D exhibited PS cytotoxicity in the range ED50 0.02-0.0023 microgram/ml.Entities:
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Year: 1982 PMID： 6126528 DOI： 10.1021/np50021a007
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050