Literature DB >> 6126028

The effect of carazolol on the cardiovascular responses to adrenaline in stress sensitive pigs.

N G Gregory, L J Wilkins.   

Abstract

The effect of propranolol, carazolol and acebutolol on the heart rate and blood pressure responses to intravenous adrenaline were examined in conscious Pietrain pigs. All three drugs blocked the tachycardia and vasodilatory responses to adrenaline and induced an increase in vasopressor responsiveness. The likely complications from using non-cardioselective beta blockers for preventing stress-induced deaths in pigs are discussed.

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Year:  1982        PMID： 6126028     DOI： 10.1007/bf02214994

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  7 in total

1.  Modification of ventricular fibrillation latency following coronary artery occlusion in the conscious pig.

Authors:  J E Skinner; J T Lie; M L Entman
Journal:  Circulation       Date:  1975-04       Impact factor: 29.690

2.  High affinity of carozolol for beta-adrenoceptors coupled to the adenylyl cyclase in ventricular myocardium of kitten and Xenopus laevis.

Authors:  T H Morris; L Birnbaumer; A J Kaumann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-07       Impact factor: 3.000

3.  Characterization of the adrenoceptors in coronary arteries of pigs.

Authors:  B L Bayer; P Mentz; W Förster
Journal:  Eur J Pharmacol       Date:  1974-11       Impact factor: 4.432

4.  The selectivity of beta-adrenoceptor antagonists on cardiovascular and bronchodilator responses to isoprenaline in the anaesthetized dog.

Authors:  M J Daly; J J Flook; G P Levy
Journal:  Br J Pharmacol       Date:  1975-02       Impact factor: 8.739

5.  Autonomic and non-autonomic control of cardiovascular function in stress-sensitive pigs.

Authors:  N G Gregory; S B Wotton
Journal:  J Vet Pharmacol Ther       Date:  1981-09       Impact factor: 1.786

6.  beta 1 Selectivity of drugs: quality of the drug or quality of the patient?

Authors:  P von Wichert; I Perkow; W Teufel
Journal:  Respiration       Date:  1980       Impact factor: 3.580

7.  Beta-adrenoceptor blocking properties and cardioselectivity of M & B 17,803A.

Authors:  B Basil; R Jordan; A H Loveless; D R Maxwell
Journal:  Br J Pharmacol       Date:  1973-06       Impact factor: 8.739
  7 in total

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