Literature DB >> 6122353

Biochemistry, pathophysiology and pharmacology of slow-reacting substances/leukotrienes.

G P Lewis.   

Abstract

The chemistry, biosynthesis and general pharmacology of leukotrienes C4 and D4 are reviewed, with emphasis on the cardiovascular and smooth muscle effects of these agents. Pathways controlling the formation of the leukotrienes are considered together with their possible pathophysiological roles.

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Year:  1981        PMID： 6122353     DOI： 10.1007/bf01978744

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  7 in total

1.  Control of vascular permeability by polymorphonuclear leukocytes in inflammation.

Authors:  C V Wedmore; T J Williams
Journal:  Nature       Date:  1981-02-19       Impact factor: 49.962

2.  The effect of leukotrienes C4 and D4 on the microvasculature of guinea-pig skin.

Authors:  M J Peck; P J Piper; T J Williams
Journal:  Prostaglandins       Date:  1981-02

3.  Slow-reacting substance of anaphylaxis: purification and characterisation.

Authors:  H R Morris; G W Taylor; P J Piper; P Sirois; J R Tippins
Journal:  FEBS Lett       Date:  1978-03-15       Impact factor: 4.124

4.  Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes.

Authors:  A W Ford-Hutchinson; M A Bray; M V Doig; M E Shipley; M J Smith
Journal:  Nature       Date:  1980-07-17       Impact factor: 49.962

5.  Leukotriene C elicits a prolonged excitation of cerebellar Purkinje neurons.

Authors:  M R Palmer; R Mathews; R C Murphy; B J Hoffer
Journal:  Neurosci Lett       Date:  1980-06       Impact factor: 3.046

6.  Structure of slow-reacting substance of anaphylaxis (SRS-A).

Authors:  H Ohnishi; H Kosuzume; Y Kitamura; K Yamaguchi; M Nobuhara; Y Suzuki; S Yoshida; H Tomioka; A Kumagai
Journal:  Prostaglandins       Date:  1980-10

7.  Mediation of increased vascular permeability after complement activation. Histamine-independent action of rabbit C5a.

Authors:  T J Williams; P J Jose
Journal:  J Exp Med       Date:  1981-01-01       Impact factor: 14.307
  7 in total
  3 in total

1.  Mechanism of leukotriene-induced contraction of isolated guinea pig tracheal smooth muscle.

Authors:  T Sasaki; K Takagi; T Satake; S Sugiyama; T Ozawa
Journal:  Lung       Date:  1984       Impact factor: 2.584

Review 2.  [Eicosanoids and phospholipases].

Authors:  M Goerig; A J Habenicht; G Schettler
Journal:  Klin Wochenschr       Date:  1985-04-01

Review 3.  Biomarkers for the Phenotyping and Monitoring of Asthma in Children.

Authors:  Anna James; Gunilla Hedlin
Journal:  Curr Treat Options Allergy       Date:  2016-10-20
  3 in total

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