Literature DB >> 6117431

The effect of antihypertensive therapy on abnormal leucocyte sodium transport in essential hypertension.

L Poston, R B Jones, P J Richardson, P J Hilton.   

Abstract

Sodium transport in leucocytes of essential hypertensives was studied in physiological media. Untreated hypertensives have depressed values for the total and ouabain-sensitive sodium efflux rate constant. Treatment with diuretics abolished this abnormality. These results are compatible with the presence of a circulating inhibitor of sodium transport in essential hypertension.

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Year:  1981        PMID: 6117431     DOI: 10.3109/10641968109033694

Source DB:  PubMed          Journal:  Clin Exp Hypertens        ISSN: 0148-3927            Impact factor:   1.749


  4 in total

1.  Hypertension symposium: newer topics on normal and abnormal blood pressure regulatory mechanisms.

Authors:  M L Tuck; M S Golub; P Eggena; J R Sowers; M Maxwell
Journal:  West J Med       Date:  1983-08

Review 2.  Diuretics and cation transport in hypertensive blacks.

Authors:  A P Quintanilla; O E Wagener
Journal:  Cardiovasc Drugs Ther       Date:  1990-03       Impact factor: 3.727

3.  Reversal by verapamil of defect in sodium transport in leucocytes in essential hypertension.

Authors:  H H Gray; L Poston; P J Hilton; S J Smith; N D Markandu; G A MacGregor
Journal:  Br Med J (Clin Res Ed)       Date:  1984-03-03

4.  Intrinsic difference in erythrocyte membrane in spontaneously hypertensive rats characterized by Na+ and K+ fluxes.

Authors:  C J van de Ven; D F Bohr
Journal:  Pflugers Arch       Date:  1983-09       Impact factor: 3.657

  4 in total

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