Literature DB >> 6115042

(--)-m-Chlorophenyl-piperazine, a central 5-hydroxytryptamine agonist, is a metabolite of trazodone.

S Caccia, M Ballabio, R Samanin, M G Zanini, S Garattini.   

Abstract

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Year:  1981        PMID： 6115042     DOI： 10.1111/j.2042-7158.1981.tb13841.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


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  23 in total

Review 1.  Metabolism of some "second"- and "fourth"-generation antidepressants: iprindole, viloxazine, bupropion, mianserin, maprotiline, trazodone, nefazodone, and venlafaxine.

Authors:  S Rotzinger; M Bourin; Y Akimoto; R T Coutts; G B Baker
Journal:  Cell Mol Neurobiol       Date:  1999-08       Impact factor: 5.046

2.  Excretion of trazodone in breast milk.

Authors:  R K Verbeeck; S G Ross; E A McKenna
Journal:  Br J Clin Pharmacol       Date:  1986-09       Impact factor: 4.335

Review 3.  Active drug metabolites. An overview of their relevance in clinical pharmacokinetics.

Authors:  S Garattini
Journal:  Clin Pharmacokinet       Date:  1985 May-Jun       Impact factor: 6.447

4.  Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.

Authors:  S P Vickers; K R Benwell; R H Porter; M J Bickerdike; G A Kennett; C T Dourish
Journal:  Br J Pharmacol       Date:  2000-07       Impact factor: 8.739

Review 5.  The Role of Metabolites of Antidepressants in the Treatment of Depression.

Authors:  M V Rudorfer; W Z Potter
Journal:  CNS Drugs       Date:  1997-04       Impact factor: 5.749

6.  Opposite action of m-chlorophenylpiperazine on avoidance depression induced by trazodone and pimozide in CD-1 mice.

Authors:  J Vetulani; M Sansone; L Baran; J Hano
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

7.  Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion.

Authors:  J Ulrichsen; J S Partilla; E M Dax
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

8.  5-HT1C receptor antagonists have anxiolytic-like actions in the rat social interaction model.

Authors:  G A Kennett
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

9.  Etoperidone, trazodone and MCPP: in vitro and in vivo identification of serotonin 5-HT1A (antagonistic) activity.

Authors:  R B Raffa; R P Shank; J L Vaught
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

10.  Different effects of 3-chlorophenylpiperazine on locomotor activity and acquisition of conditioned avoidance response in different strains of mice.

Authors:  J Vetulani; M Sansone; B Bednarczyk; J Hano
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-06       Impact factor: 3.000
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