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Literature DB >> 6112389

Some patients with cerebral aneurysms are deficient in type III collagen.

F M Pope, A C Nicholls, P Narcisi, J Bartlett, G Neil-Dwyer, B Doshi.

Abstract

Polyacrylamide gel electrophoresis of pepsin-digested skin biopsy specimens and carboxymethyl cellulose chromatography of radioactively labelled collagens produced by cultured fibroblasts demonstrated that 7 of 12 patients with congenital cerebral aneurysms were type III collagen deficient. This suggests that some cerebral aneurysms resemble various inherited defects of connective tissue-i.e., Ehlers-Danlos syndrome type IV-in which type III collagen deficiency causes arterial fragility.

Entities: Chemical Disease Species

Mesh：

Substances：
Collagen

Year: 1981 PMID： 6112389 DOI： 10.1016/s0140-6736(81)91735-9

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

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Cited

20 in total

1. Experimental cerebral aneurysms in the female heterozygous Blotchy mouse.

Authors: M Coutard
Journal: Int J Exp Pathol Date: 1999-12 Impact factor: 1.925

Review 2. Prenatal diagnosis and prevention of inherited abnormalities of collagen.

Authors: F M Pope; S C Daw; P Narcisi; A R Richards; A C Nicholls
Journal: J Inherit Metab Dis Date: 1989 Impact factor: 4.982

3. Vasospasm and the timing of aneurysm surgery; have we progressed?

Authors: E S Flamm
Journal: Neurosurg Rev Date: 1986 Impact factor: 3.042

4. Intracranial aneurysm with concomitant rupture of an undiagnosed visceral artery aneurysm.

Authors: William R Stetler; Aditya S Pandey; George A Mashour
Journal: Neurocrit Care Date: 2012-02 Impact factor: 3.210

5. Abdominal aortic aneurysms: distribution of elastin, collagen I and III, and intermediate filament proteins desmin and vimentin--a comparison of familial and nonfamilial aneurysms.

Authors: L E Thornell; O Norrgård; A Eriksson; M Vanderwee; K A Angqvist
Journal: Heart Vessels Date: 1986 Impact factor: 2.037

Some patients with cerebral aneurysms are deficient in type III collagen.

1. Experimental cerebral aneurysms in the female heterozygous Blotchy mouse.

Review 2. Prenatal diagnosis and prevention of inherited abnormalities of collagen.

3. Vasospasm and the timing of aneurysm surgery; have we progressed?

4. Intracranial aneurysm with concomitant rupture of an undiagnosed visceral artery aneurysm.

5. Abdominal aortic aneurysms: distribution of elastin, collagen I and III, and intermediate filament proteins desmin and vimentin--a comparison of familial and nonfamilial aneurysms.

6. Histological pattern and changes in extracellular matrix in aortic dissections.

7. Subarachnoid haemorrhage in identical twins.

8. mRNA expression in rabbit experimental aneurysms: a study using gene chip microarrays.

9. Mitral valve prolapse, aortic compliance, and skin collagen in joint hypermobility syndrome.

10. Ethnic distribution of intracranial aneurysms.