Literature DB >> 6109799

Association between failure to impregnate after vasovasostomy and sperm agglutinins in semen.

L Linnet, T Hjort, P Fogh-Andersen.   

Abstract

Sperm agglutinins emerging from the reopened part of the vas deferens were found in the seminal fluid of 10 out of 29 men after vasovasostomy. There was a strong association between the presence of these antibodies and the failure to impregnate over a period of 14 to 33 months. Of 20 couples, 11 pregnancies resulted among the 13 women whose men had no sperm agglutinins in the seminal fluid, but only 1 among the 7 whose men had such antibodies, 2p = 0.0044. The presence of sperm agglutinins in the seminal fluid was always associated with their presence in the serum, usually in a higher titre. Preoperative serum levels thus are highly predictive of ability to impregnate after reversal of vasectomy.

Entities:  

Keywords:  Antibodies--analysis; Biology; Correlation Studies; Evaluation; Family Planning; Follow-up Studies; Genitalia; Genitalia, Male; Germ Cells; Immunity; Immunologic Factors; Infertility; Male Sterilization; Physiology; Reproduction; Research Methodology; Reversibility; Reversible Sterilization; Semen; Seminal Vesicles; Spermatozoa; Statistical Studies; Sterilization Reversal; Sterilization, Sexual; Studies; Urogenital System; Use-effectiveness; Vas Reanastomosis

Mesh:

Substances:

Year:  1981        PMID: 6109799     DOI: 10.1016/s0140-6736(81)90708-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  7 in total

1.  Analysis of the autoimmune epitopes on human testicular NASP using recombinant and synthetic peptides.

Authors:  I N Batova; R T Richardson; E E Widgren; M G O'Rand
Journal:  Clin Exp Immunol       Date:  2000-08       Impact factor: 4.330

2.  Vasectomy and the human testis.

Authors:  S W McDonald
Journal:  BMJ       Date:  1990-09-29

3.  The black mink (Mustela vison). A natural model of immunologic male infertility.

Authors:  K S Tung; L Ellis; C Teuscher; A Meng; J C Blaustein; S Kohno; R Howell
Journal:  J Exp Med       Date:  1981-10-01       Impact factor: 14.307

4.  Vasectomy reversal.

Authors:  M R Young; C J Logan
Journal:  Ulster Med J       Date:  1989-10

Review 5.  Predictors of success in microsurgical correction of vasal and epididymal obstruction.

Authors:  A M Belker
Journal:  Curr Urol Rep       Date:  2001-12       Impact factor: 2.862

Review 6.  Vasectomy reversal: a clinical update.

Authors:  Abhishek P Patel; Ryan P Smith
Journal:  Asian J Androl       Date:  2016 May-Jun       Impact factor: 3.285

Review 7.  An overview of the management of post-vasectomy pain syndrome.

Authors:  Wei Phin Tan; Laurence A Levine
Journal:  Asian J Androl       Date:  2016 May-Jun       Impact factor: 3.285

  7 in total

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