Literature DB >> 6108853

Elevated liver gamma-glutamyl transferase in chronic alcoholics.

E Ivanov, D Adjarov, M Etarska, T Stankushev, K Brumbarov, M Kerimova.   

Abstract

The activity of gamma-glutamyl transferase (gamma-GT) in the liver of 36 chronic alcoholics was twice as high as in the control group. The elevation was of the same order in cases with and without hepatic lesions. However, the activity of gamma-GT in the sera of alcoholic patients with chronic hepatitis and liver cirrhosis was significantly higher than in the remaining alcoholics. There was no correlation between the enzyme activities in the liver and in the serum of the patients examined. Consequently, the determination of liver gamma-GT activity bears no clinical significance in chronic alcoholics.

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Year:  1980        PMID: 6108853     DOI: 10.1159/000459271

Source DB:  PubMed          Journal:  Enzyme        ISSN: 0013-9432


  8 in total

Review 1.  Alcoholic foamy degeneration and a markedly elevated GGT: a case report and literature review.

Authors:  Sanjeev Suri; Frank A Mitros; Jatinder P Ahluwalia
Journal:  Dig Dis Sci       Date:  2003-06       Impact factor: 3.199

Review 2.  Is serum gamma-glutamyltransferase a misleading test?

Authors:  R Penn; D J Worthington
Journal:  Br Med J (Clin Res Ed)       Date:  1983-02-12

Review 3.  Alcohol and gamma-glutamyltransferase.

Authors:  M Nishimura; R Teschke
Journal:  Klin Wochenschr       Date:  1983-03-15

Review 4.  Clinical use of serum enzymes in liver disease.

Authors:  J J Reichling; M M Kaplan
Journal:  Dig Dis Sci       Date:  1988-12       Impact factor: 3.199

5.  Clinical importance of gamma glutamyltransferase in the Ankara-Pursaklar region of Turkey.

Authors:  Oğuz Tekin; Cem Uraldi; Bünyamin Işik; Adem Ozkara; Yasemin Ardiçoğlu; Elife Erarslan
Journal:  MedGenMed       Date:  2004-01-23

6.  Biological markers and therapeutic outcome in alcoholic disease: a twelve-year survey.

Authors:  R Fantozzi; L Caramelli; F Ledda; F Moroni; E Masini; P Blandina; P Botti; S Peruzzi; A M Zorn; P F Mannaioni
Journal:  Klin Wochenschr       Date:  1987-01-05

7.  Hepatic gamma-glutamyltransferase activity in alcoholic fatty liver: comparison with other liver enzymes in man and rats.

Authors:  R Teschke; M Neuefeind; M Nishimura; G Strohmeyer
Journal:  Gut       Date:  1983-07       Impact factor: 23.059

8.  The Serum Profile of Transferrin Isoforms in Pancreatitis.

Authors:  Agnieszka Mucha; Malgorzata Zaczek; Michal Kralisz; Ewa Gruszewska; Bogdan Cylwik; Anatol Panasiuk; Lech Chrostek
Journal:  J Clin Med       Date:  2022-03-16       Impact factor: 4.241

  8 in total

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