Literature DB >> 15208516

Clinical importance of gamma glutamyltransferase in the Ankara-Pursaklar region of Turkey.

Oğuz Tekin1, Cem Uraldi, Bünyamin Işik, Adem Ozkara, Yasemin Ardiçoğlu, Elife Erarslan.   

Abstract

OBJECTIVE: The aim of this study is to determine the etiologies of serum gamma glutamyltransferase (GGT) elevation and relations between multiple etiologies prevalent in the Pursaklar region of Ankara in Turkey. PATIENTS AND METHODS: The patients referred to the Family Medicine and Internal Medicine departments with various complaints from the Pursaklar region of Ankara between July 2000 and July 2002 were evaluated, and values for GGT, alkaline phosphatase (ALP), and alanine aminotransferase (ALT) levels were determined. GGT elevation was classified as being associated with hepatic, biliary, and other origins.
RESULTS: For GGT elevation, hepatobiliary etiologies were more prevalent. The most prevalent hepatic etiology was nonalcoholic steatohepatitis, followed by biliary etiologies. The most prevalent etiology of biliary origin was cholelithiasis. Other etiologies, in order of prevalence, were drug exposure and urinary infection. There were no gender-related differences for distribution of GGT elevation; however, the GGT values for women were higher than those for men.

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Year:  2004        PMID: 15208516      PMCID: PMC1140713     

Source DB:  PubMed          Journal:  MedGenMed        ISSN: 1531-0132


  7 in total

1.  Serum gamma-glutamyl transpeptidase. Evaluation in screening of hospitalized patients.

Authors:  S Burrows; W Feldman; F McBride
Journal:  Am J Clin Pathol       Date:  1975-09       Impact factor: 2.493

2.  Value of serum gamma-glutamyltransferase activity in the diagnosis of hepatobiliary disease.

Authors:  D C Ruppin; M I Frydman; M R Lunzer
Journal:  Med J Aust       Date:  1982-05-15       Impact factor: 7.738

3.  Elevated liver gamma-glutamyl transferase in chronic alcoholics.

Authors:  E Ivanov; D Adjarov; M Etarska; T Stankushev; K Brumbarov; M Kerimova
Journal:  Enzyme       Date:  1980

4.  Serum gamma-glutamyl transpeptidase: its specificity and clinical value.

Authors:  M Levinson; J Holbert; C Blackwell; L D Wruble
Journal:  South Med J       Date:  1979-07       Impact factor: 0.954

Review 5.  Gamma-glutamyltransferase: value of its measurement in paediatrics.

Authors:  Jose C Cabrera-Abreu; Anne Green
Journal:  Ann Clin Biochem       Date:  2002-01       Impact factor: 2.057

6.  gamma-Glutamyl transpeptidase activity in liver disease: serum elevation is independent of hepatic GGTP activity.

Authors:  M J Selinger; D S Matloff; M M Kaplan
Journal:  Clin Chim Acta       Date:  1982-11-10       Impact factor: 3.786

7.  Ethanol effects in a rat hepatoma cell line: induction of gamma-glutamyltransferase.

Authors:  R Barouki; M N Chobert; J Finidori; M Aggerbeck; B Nalpas; J Hanoune
Journal:  Hepatology       Date:  1983 May-Jun       Impact factor: 17.425

  7 in total

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