Literature DB >> 6108538

Immunohistological localization of gamma-glutamyltranspeptidase in cerebellum at light and electron microscope levels.

M S Ghandour, O K Langley, V Varga.   

Abstract

An immune serum directed against the purified form of gamma-glutamyltranspeptidase from rat kidney cross-reacts with brain extract. An immunohistological study in rat cerebellum showed that the endothelial cells of blood vessels are heavily stained for the enzyme. Immunoelectron microscopy revealed high concentration of gamma-glutamyltranspeptidase on the luminal surface of cell membrane of endothelial cells, a possible site of the blood-brain barrier for amino acids.

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Year:  1980        PMID： 6108538     DOI： 10.1016/0304-3940(80)90133-0

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  10 in total

Review 1.  Apicobasal polarity of brain endothelial cells.

Authors:  Thomas Worzfeld; Markus Schwaninger
Journal:  J Cereb Blood Flow Metab       Date:  2015-10-06       Impact factor: 6.200

2.  Brain gamma-glutamyltranspeptidase: characteristics, development and thyroid hormone dependency of the enzyme in isolated microvessels and neuronal/glial cell plasma membranes.

Authors:  S J Hemmings; K B Storey
Journal:  Mol Cell Biochem       Date:  1999-12       Impact factor: 3.396

Review 3.  Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy.

Authors:  Eain M Cornford; Shigeyo Hyman
Journal:  NeuroRx       Date:  2005-01

Review 4.  [The blood-brain barrier: a specialty of cerebral microcirculation systems].

Authors:  S Wolf; B Seehaus; K Minol; H G Gassen
Journal:  Naturwissenschaften       Date:  1996-07

5.  The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture.

Authors:  R Dringen; O Kranich; B Hamprecht
Journal:  Neurochem Res       Date:  1997-06       Impact factor: 3.996

6.  A new method of lectin histochemistry for the study of brain angiogenesis. Lectin angiography.

Authors:  T Minamikawa; T Miyake; T Takamatsu; S Fujita
Journal:  Histochemistry       Date:  1987

7.  Effects of short-term and prolonged aerogenic hypoxia on gamma-glutamyl transpeptidase activity in the brain, liver, and biological fluids of young rats.

Authors:  F Stastný; V Lisý; H Tomásová; S Trojan
Journal:  Neurochem Res       Date:  1985-06       Impact factor: 3.996

8.  Monoclonal antibodies as neural cell surface markers.

Authors:  O K Langley; M S Ghandour; G Gombos; M Hirn; C Goridis
Journal:  Neurochem Res       Date:  1982-03       Impact factor: 3.996

9.  Carbonic anhydrase IV on brain capillary endothelial cells: a marker associated with the blood-brain barrier.

Authors:  M S Ghandour; O K Langley; X L Zhu; A Waheed; W S Sly
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

10.  Quantitative detection of blood-brain barrier-associated enzymes in cultured endothelial cells of porcine brain microvessels.

Authors:  H Fukushima; M Fujimoto; M Ide
Journal:  In Vitro Cell Dev Biol       Date:  1990-06
  10 in total

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