Patients appreciate premedication for endoscopy.

Upper gastrointestinal endoscopy without sedation by means of a small diameter (9 mm) instrument is feasible but patients often remember the procedure as unpleasant, do not wish to have it repeated, and compare it unfavourably with a barium meal. In contrast, endoscopy with a larger instrument (13 mm) after diazepam sedation is usually well tolerated and often regarded as no more uncomfortable than a barium meal. Even when a narrow instrument is used, patients still benefit from premedication with diazepam, although return to normal activity is slower because of drowsiness.

RCT Entities:   Population Interventions Outcomes