Literature DB >> 6104669

Leukotriene C5: a slow reacting substance derived from eicosapentaenoic acid.

S Hammarström.   

Abstract

Mouse mastocytoma cells incubated with ionophore A23187 and eicosapentaenoic acid (n-3) produced a slow reacting substance with different properties compared with leukotriene C4 (previously designated leukotriene C). This product was characterized by spectroscopy and enzymatic and chemical degradations to be 5-hydroxy-6-S-glutathionyl-7,9,11,14,17-eicosapentaenoic acid (leukotriene C5). Leukotriene C5 has similar biological activity on the isolated guinea pig ileum but is less potent than is leukotriene C4.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6104669

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  12 in total

1.  Modulation of the contractile activity of the guinea-pig lung parenchymal strip by exogenous 5,8,11,14,17-eicosapentaenoic acid.

Authors:  T Simmet; J Aissa; D Sutter; H Juan; B A Peskar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-06       Impact factor: 3.000

Review 2.  Nutrition and autoimmunity: a review.

Authors:  J Homsy; W J Morrow; J A Levy
Journal:  Clin Exp Immunol       Date:  1986-09       Impact factor: 4.330

3.  Properties of highly purified leukotriene C4 synthase of guinea pig lung.

Authors:  T Yoshimoto; R J Soberman; B Spur; K F Austen
Journal:  J Clin Invest       Date:  1988-03       Impact factor: 14.808

4.  Enhanced production of IgE and IgG antibodies associated with a diet enriched in eicosapentaenoic acid.

Authors:  J D Prickett; D R Robinson; K J Bloch
Journal:  Immunology       Date:  1982-08       Impact factor: 7.397

5.  Immunopathogenetic roles of leukotrienes in human diseases.

Authors:  E J Goetzl; D G Payan; D W Goldman
Journal:  J Clin Immunol       Date:  1984-03       Impact factor: 8.317

Review 6.  Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs.

Authors:  Melissa Gabbs; Shan Leng; Jessay G Devassy; Md Monirujjaman; Harold M Aukema
Journal:  Adv Nutr       Date:  2015-09-15       Impact factor: 8.701

7.  Influence of dietary fat composition on intestinal absorption in the rat.

Authors:  A B Thomson; M Keelan; M L Garg; M T Clandinin
Journal:  Lipids       Date:  1989-06       Impact factor: 1.880

8.  Release of a slow-reacting substance from rabbit platelets.

Authors:  J M Mencia-Huerta; L Hadji; J Benveniste
Journal:  J Clin Invest       Date:  1981-12       Impact factor: 14.808

9.  Arachidonic acid and eicosapentaenoic acid stimulate type II pneumocyte surfactant secretion.

Authors:  R C Baybutt; J E Smith; M N Gillespie; T G Newcomb; Y Y Yeh
Journal:  Lipids       Date:  1994-08       Impact factor: 1.880

10.  Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.

Authors:  T H Lee; J M Mencia-Huerta; C Shih; E J Corey; R A Lewis; K F Austen
Journal:  J Clin Invest       Date:  1984-12       Impact factor: 14.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.