Literature DB >> 6102691

The Halcion story: trial by media.

L Lasagna.   

Abstract

Triazolam ('Halcion'), a benzodiazepine sedative-hypnotic, has been alleged to produce unique and serious adverse effects on the central nervous system. In the Netherlands television and newspaper coverage of reported side-effects was followed by a temporary suspension of the drug there. The reported adverse reactions resemble ones known to occur occasionally after older benzodiazepines and other central nervous system drugs. Whatever the final verdict on triazolam may be, there is reason to question whether regulatory decisions forced by flamboyant media coverage are in the public interest.

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Year:  1980        PMID: 6102691     DOI: 10.1016/s0140-6736(80)91306-9

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  6 in total

1.  Drug related admissions to medical wards: a population based survey.

Authors:  J Hallas; L F Gram; E Grodum; N Damsbo; K Brøsen; T Haghfelt; B Harvald; J Beck-Nielsen; J Worm; K B Jensen
Journal:  Br J Clin Pharmacol       Date:  1992-01       Impact factor: 4.335

2.  Drug innovation bureaucracy.

Authors: 
Journal:  Br Med J       Date:  1980-06-21

3.  Sublingual triazolam versus peroral diazepam as a premedication for general anaesthesia.

Authors:  H J Penttilä; L S Nuutinen; K T Kiviluoma; A M Partanen
Journal:  Can J Anaesth       Date:  1995-10       Impact factor: 5.063

Review 4.  Hallucinations and delirium in the dental office following triazolam administration.

Authors:  Jason H Goodchild; Mark Donaldson
Journal:  Anesth Prog       Date:  2005

5.  Spontaneous Adverse Event Reports Associated with Zolpidem in the United States 2003-2012.

Authors:  Carmen K Wong; Nathaniel S Marshall; Ronald R Grunstein; Samuel S Ho; Romano A Fois; David E Hibbs; Jane R Hanrahan; Bandana Saini
Journal:  J Clin Sleep Med       Date:  2017-02-15       Impact factor: 4.062

Review 6.  Triazolam: a review of its pharmacological properties and therapeutic efficacy in patients with insomnia.

Authors:  G E Pakes; R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1981-08       Impact factor: 9.546

  6 in total

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