Literature DB >> 6098333

Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices.

M Goedert, R D Pinnock, C P Downes, P W Mantyh, P C Emson.   

Abstract

Neurotensin stimulated inositol phospholipid hydrolysis in matched coronal vibratome sections through the rat brain. This effect was tetrodotoxin-resistant and a good correlation was noticed between the magnitude of neurotensin-stimulated inositol phospholipid hydrolysis and the number of specific [3H]neurotensin binding sites in various brain regions. Neurotensin produced no significant effect on either basal or stimulated cAMP levels.

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Year:  1984        PMID: 6098333     DOI: 10.1016/0006-8993(84)90288-9

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  11 in total

Review 1.  Receptor-receptor interactions as an integrative mechanism in nerve cells.

Authors:  M Zoli; L F Agnati; P B Hedlund; X M Li; S Ferré; K Fuxe
Journal:  Mol Neurobiol       Date:  1993 Fall-Winter       Impact factor: 5.590

2.  Regulation of phosphatidylinositol turnover in brain synaptoneurosomes: stimulatory effects of agents that enhance influx of sodium ions.

Authors:  F Gusovsky; E B Hollingsworth; J W Daly
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

3.  Proceedings of the British Pharmacological Society. Leeds, 12th-14th July 1989. Abstracts.

Authors: 
Journal:  Br J Pharmacol       Date:  1989-10       Impact factor: 8.739

4.  Neurotensin excites basal forebrain cholinergic neurons: ionic and signal-transduction mechanisms.

Authors:  R H Farkas; S Nakajima; Y Nakajima
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-29       Impact factor: 11.205

5.  Characterization of high affinity neurotensin receptor NTR1 in HL-60 cells and its down regulation during granulocytic differentiation.

Authors:  S Y Choi; H D Chae; T J Park; H Ha; K T Kim
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

Review 6.  Neurotensin receptors: binding properties, transduction pathways, and structure.

Authors:  J P Vincent
Journal:  Cell Mol Neurobiol       Date:  1995-10       Impact factor: 5.046

7.  Neurotensin stimulates inositol trisphosphate-mediated calcium mobilization but not protein kinase C activation in HT29 cells. Involvement of a G-protein.

Authors:  J C Bozou; N Rochet; I Magnaldo; J P Vincent; P Kitabgi
Journal:  Biochem J       Date:  1989-12-15       Impact factor: 3.857

8.  Characterization of the effect of SR48692 on inositol monophosphate, cyclic GMP and cyclic AMP responses linked to neurotensin receptor activation in neuronal and non-neuronal cells.

Authors:  F Oury-Donat; O Thurneyssen; N Gonalons; P Forgez; D Gully; G Le Fur; P Soubrie
Journal:  Br J Pharmacol       Date:  1995-09       Impact factor: 8.739

9.  Neurotensin excitation of rat ventral tegmental neurones.

Authors:  Z G Jiang; M Pessia; R A North
Journal:  J Physiol       Date:  1994-01-01       Impact factor: 5.182

10.  Expression of a rat neurotensin receptor in Escherichia coli.

Authors:  R Grisshammer; R Duckworth; R Henderson
Journal:  Biochem J       Date:  1993-10-15       Impact factor: 3.857

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