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Literature DB >> 6096826

Transfer RNA splicing in Saccharomyces cerevisiae: defining the substrates.

Abstract

The primary sequences of all the tRNA precursors which contain intervening sequences and which accumulate in the Saccharomyces cerevisiae rnal mutant are presented. A combination of DNA and RNA sequence analysis has led to elucidation of the primary sequence of four hitherto uncharacterized precursors. The location of the intervening sequence has in all cases been unambiguously determined by analysis of the intermediates in the splicing reaction. Secondary structures based upon the tRNA cloverleaf are shown for all the tRNA precursors and discussed with respect to common recognition by the yeast splicing endonuclease.

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Year: 1984 PMID： 6096826 PMCID： PMC320467 DOI： 10.1093/nar/12.24.9367

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

32 in total

1. A new method for sequencing DNA.

Authors: A M Maxam; W Gilbert
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

2. Structure and processing of yeast precursor tRNAs containing intervening sequences.

Authors: P Z O'Farrell; B Cordell; P Valenzuela; W J Rutter; H M Goodman
Journal: Nature Date: 1978-08-03 Impact factor: 49.962

3. A yeast mutant which accumulates precursor tRNAs.

Authors: A K Hopper; F Banks
Journal: Cell Date: 1978-06 Impact factor: 41.582

4. Transcription and processing of intervening sequences in yeast tRNA genes.

Authors: G Knapp; J S Beckmann; P F Johnson; S A Fuhrman; J Abelson
Journal: Cell Date: 1978-06 Impact factor: 41.582

5. Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o.

Authors: H M Goodman; M V Olson; B D Hall
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

6. Structure of yeast phenylalanine-tRNA genes: an intervening DNA segment within the region coding for the tRNA.

Authors: P Valenzuela; A Venegas; F Weinberg; R Bishop; W J Rutter
Journal: Proc Natl Acad Sci U S A Date: 1978-01 Impact factor: 11.205

7. The nucleotide sequences and coding properties of the major and minor lysine transfer ribonucleic acids from the haploid yeast Saccharomyces cerevisiae S288C.

Authors: C J Smith; H S Teh; A N Ley; P D'Obrenan
Journal: J Biol Chem Date: 1973-06-25 Impact factor: 5.157

3. Construction of an opal suppressor by oligonucleotide-directed mutagenesis of a Saccharomyces cerevisiae tRNA(Trp) gene.

Authors: A L Atkin; K L Roy; J B Bell
Journal: Mol Cell Biol Date: 1990-08 Impact factor: 4.272

Transfer RNA splicing in Saccharomyces cerevisiae: defining the substrates.

1. A new method for sequencing DNA.

2. Structure and processing of yeast precursor tRNAs containing intervening sequences.

3. A yeast mutant which accumulates precursor tRNAs.

4. Transcription and processing of intervening sequences in yeast tRNA genes.

5. Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o.

6. Structure of yeast phenylalanine-tRNA genes: an intervening DNA segment within the region coding for the tRNA.

7. The nucleotide sequences and coding properties of the major and minor lysine transfer ribonucleic acids from the haploid yeast Saccharomyces cerevisiae S288C.

8. Improved estimation of secondary structure in ribonucleic acids.

Review 9. Sequence and structure analysis of end-labeled RNA with nucleases.

10. DNA sequencing with chain-terminating inhibitors.

1. Structural investigation of the in vitro transcript of the yeast tRNA(phe) precursor by NMR and nuclease mapping.

2. Preferential binding of yeast tRNA ligase to pre-tRNA substrates.

3. Construction of an opal suppressor by oligonucleotide-directed mutagenesis of a Saccharomyces cerevisiae tRNA(Trp) gene.

4. A highly specific phosphatase from Saccharomyces cerevisiae implicated in tRNA splicing.

5. Pleiotropic effects of intron removal on base modification pattern of yeast tRNAPhe: an in vitro study.

6. Plant nuclear tRNA(Met) genes are ubiquitously interrupted by introns.

7. All human tRNATyr genes contain introns as a prerequisite for pseudouridine biosynthesis in the anticodon.

8. Isolation of a yeast gene involved in species-specific pre-tRNA processing.

9. Intron mutations affect splicing of Saccharomyces cerevisiae SUP53 precursor tRNA.

10. Effect of intron mutations on processing and function of Saccharomyces cerevisiae SUP53 tRNA in vitro and in vivo.