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Literature DB >> 6096134

Encephalomyocarditis virus RNA synthesis in vitro is protein-primed.

A B Vartapetian, E V Koonin, V I Agol, A A Bogdanov.

Abstract

A crude membrane-bound replication complex isolated from encephalomyocarditis virus-infected cells is able to initiate the synthesis of viral RNA. Both the formation of the primer, VPg-pU, and its utilization for the initiation of RNA chains take place in this system. A significant amount of the synthesized VPg-pU is found in the free form. The predominant product of the de novo initiation is represented by short phenol-soluble VPg oligonucleotide species, and only a small percentage of the latter appear to be elongated into longer RNA chains.

Entities: Chemical

Mesh：

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Year: 1984 PMID： 6096134 PMCID： PMC557735 DOI： 10.1002/j.1460-2075.1984.tb02179.x

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

26 in total

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Journal: Mol Biol (Mosk) Date: 1979 Jul-Aug

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Journal: Cell Date: 1978-12 Impact factor: 41.582

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Authors: R F Pettersson; V Ambros; D Baltimore
Journal: J Virol Date: 1978-08 Impact factor: 5.103

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Authors: J B Flanegan; R F Petterson; V Ambros; N J Hewlett; D Baltimore
Journal: Proc Natl Acad Sci U S A Date: 1977-03 Impact factor: 11.205

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Authors: A Nomoto; B Detjen; R Pozzatti; E Wimmer
Journal: Nature Date: 1977-07-21 Impact factor: 49.962

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Authors: K M Chumakov
Journal: Biokhimiia Date: 1979-01

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Authors: T M Dmitrieva; V I Agol
Journal: Arch Gesamte Virusforsch Date: 1974

8. Fluorescence monitoring of unstained protein bands in acrylamide gel.

Authors: D M Easton; H Lipner; J Hines; R C Leif
Journal: Anal Biochem Date: 1971-02 Impact factor: 3.365

9. The enzymatic preparation of [alpha-32P]ATP, [alpha-32P]GTP, [32P]cAMP, and [32P]cGMP, and their use in the assay of adenylate and guanylate cyclases and cyclic nucleotide phosphodiesterases.

Authors: R A Johnson; T F Walseth
Journal: Adv Cyclic Nucleotide Res Date: 1979

3. Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: purification and enzymatic analysis of the RNA-dependent RNA polymerase 3D(pol).

Authors: K Gerber; E Wimmer; A V Paul
Journal: J Virol Date: 2001-11 Impact factor: 5.103

4. Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro).