Literature DB >> 196204

The location of the polio genome protein in viral RNAs and its implication for RNA synthesis.

A Nomoto, B Detjen, R Pozzatti, E Wimmer.   

Abstract

Evidence is presented that a small protein (VPg) is covalently attached to the 5'-terminal oligonucleotide VPg-pU-U-A-A-A-A-C-A-Gp of the polio genome, to nascent strands of the polio replicative intermediate and to poly(U) of minus strands. A model of polio RNA replication is proposed implicating VPg in initiation of RNA symthesis, possibly as primer.

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Year:  1977        PMID： 196204     DOI： 10.1038/268208a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  114 in total

1.  Phenotypic characterization of three phylogenetically conserved stem-loop motifs in the mengovirus 3' untranslated region.

Authors:  H Duque; A C Palmenberg
Journal:  J Virol       Date:  2001-04       Impact factor: 5.103

2.  cis-acting lesions targeted to the hydrophobic domain of a poliovirus membrane protein involved in RNA replication.

Authors:  C Giachetti; S S Hwang; B L Semler
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

3.  Linker scanning mutagenesis of the internal ribosome entry site of poliovirus RNA.

Authors:  A A Haller; B L Semler
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

4.  A convenient sequencing method for 5' protein-linked RNAs.

Authors:  A Nomoto; N Imura
Journal:  Nucleic Acids Res       Date:  1979-11-10       Impact factor: 16.971

5.  An electron microscope study of the proteins attached to polio virus RNA and its replicative form (RF).

Authors:  M Wu; N Davidson; E Wimmer
Journal:  Nucleic Acids Res       Date:  1978-12       Impact factor: 16.971

6.  Isolation and preliminary characterization of temperature-sensitive mutants of encephalomyocarditis virus.

Authors:  R J Radloff
Journal:  J Virol       Date:  1978-07       Impact factor: 5.103

7.  Identification of specific fragments containing the 5' end of poliovirus RNA after ribonuclease III digestion.

Authors:  T J Harris; J J Dunn; E Wimmer
Journal:  Nucleic Acids Res       Date:  1978-11       Impact factor: 16.971

8.  Identification of a protein linked to nascent poliovirus RNA and to the polyuridylic acid of negative-strand RNA.

Authors:  R F Pettersson; V Ambros; D Baltimore
Journal:  J Virol       Date:  1978-08       Impact factor: 5.103

9.  A new cis-acting element for RNA replication within the 5' noncoding region of poliovirus type 1 RNA.

Authors:  K Shiroki; T Ishii; T Aoki; M Kobashi; S Ohka; A Nomoto
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

10.  Poliovirus protein 3AB forms a complex with and stimulates the activity of the viral RNA polymerase, 3Dpol.

Authors:  S J Plotch; O Palant
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103
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