Literature DB >> 6095745

Kindling: an animal model of complex partial epilepsy.

J O McNamara.   

Abstract

Kindling is an animal model of complex partial epilepsy induced by focal electrical stimulation of the brain. This paper describes the phenomenon and underscores the limited nature of current insights into its basic mechanisms. Anatomical delineation of the underlying neural network is a necessary first step for elucidating the basic cellular and molecular mechanisms. Recent evidence suggests that the substantia nigra may be a crucial component of the network underlying limbic kindled seizures and possibly kindling itself.

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Year:  1984        PMID： 6095745     DOI： 10.1002/ana.410160712

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  15 in total

Review 1.  Pictorial review of glutamate excitotoxicity: fundamental concepts for neuroimaging.

Authors:  L P Mark; R W Prost; J L Ulmer; M M Smith; D L Daniels; J M Strottmann; W D Brown; L Hacein-Bey
Journal:  AJNR Am J Neuroradiol       Date:  2001 Nov-Dec       Impact factor: 3.825

2.  Limbic epileptogenesis: a model study using kindling from the amygloid cortical nucleus.

Authors:  A F Bikbaev; A V Karpova; S A Chepurnov; N E Chepurnova; L B Kalimullina
Journal:  Dokl Biol Sci       Date:  2002 Mar-Apr

3.  Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.

Authors:  Trevor H Gilbert; G Campbell Teskey
Journal:  Exp Brain Res       Date:  2007-01-26       Impact factor: 1.972

Review 4.  Complex metabolically demanding sensory processing in the olfactory system: implications for epilepsy.

Authors:  Diego Restrepo; Jennifer L Hellier; Ernesto Salcedo
Journal:  Epilepsy Behav       Date:  2013-10-07       Impact factor: 2.937

5.  The postnatal development of stimulated deoxyglucose uptake into the mouse cochlea and the inferior colliculus.

Authors:  B Canlon; M Anniko
Journal:  Arch Otorhinolaryngol       Date:  1987

6.  Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models.

Authors:  R Bernasconi; C Marescaux; M Vergnes; K Klebs; M Klein; P Martin; C Portet; L Maitre; M Schmutz
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575

7.  Pentylenetetrazol-kindling in mice overexpressing heat shock protein 70.

Authors:  Susanne Ammon-Treiber; Gisela Grecksch; Charalampos Angelidis; Patra Vezyraki; Volker Höllt; Axel Becker
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2007-02-28       Impact factor: 3.000

8.  Transmitter amino acid levels in rat brain regions after amygdala-kindling or chronic electrode implantation without kindling: evidence for a pro-kindling effect of prolonged electrode implantation.

Authors:  W Löscher; D Hörstermann; D Hönack; C Rundfeldt; U Wahnschaffe
Journal:  Neurochem Res       Date:  1993-07       Impact factor: 3.996

9.  Competitive NMDA receptor antagonists raise electrically kindled generalized seizure thresholds.

Authors:  M J Croucher; K L Cotterell; H F Bradford
Journal:  Neurochem Res       Date:  1992-05       Impact factor: 3.996

10.  Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy.

Authors:  D I Barry; I Kikvadze; P Brundin; T G Bolwig; A Björklund; O Lindvall
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205
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