| Literature DB >> 6095089 |
J de Villiers, W Schaffner, C Tyndall, S Lupton, R Kamen.
Abstract
Sequences which activate polyoma virus DNA replication are located within a region that also includes the transcriptional enhancer. We demonstrate a cis involvement of enhancers in DNA replication by showing that this region can be replaced by other enhancers, in a position- and orientation-independent manner, and that an immunoglobulin gene enhancer confers tissue-specific replicatory ability.Mesh:
Substances:
Year: 1984 PMID: 6095089 DOI: 10.1038/312242a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962